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How These Five Remedies Stop Persistent Gut Problems Caused by Listeria in People with Lyme Disease

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hitchhiker_seeds

For people with Lyme disease that have recurring digestion problems, leaky gut, or small intestine bacterial overgrowth (SIBO)
by Greg Lee

I used to play football and baseball with other neighborhood boys at Mr. Johnson’s field. Occasionally we’d have to go looking for one of our balls at the far end of the field which had tall grass and weeds. Sometimes I’d come out with “hitchhiker” weed seeds clinging to my clothes.

How are hitchhiker seeds similar to people with Lyme disease that have chronic digestion problems?

Just like seeds that sneak on to your clothes, Listeria can be a dangerous pathogen which sneaks into the intestines
In several different recalls of food products, Listeria monocytogenes was cited as a contaminant in multiple food processing plants which produce frozen food, fruit, ice cream, cheese, and sunflower seeds. In another incidence, Listeria was found in whole cantaloupes that ended up sickening 147 people and resulted in 43 fatalities[1]. According to one CDC report, Listeria can be fatal in 21% of cases[2] even despite early antibiotic treatment[3]. Fatality may be as high as 40-60% in patients with a central nervous system infection and concurrent debilitating disease[4]. People over 65, pregnant women and especially their unborn children, and immune compromised patients like people with chronic Lyme or co-infections are at greater risk. Fortunately, the risk of getting a Listeria infection is low, about 2-3 people per million in the US. However, the risk is greater in immune compromised people, even at low doses of Listeria contamination on food[5]. This infection usually starts with symptoms in the digestion system.

Listeria often presents with bloating, nausea, and diarrhea
This infection can produce symptoms of fever and muscle aches, sometimes preceded by diarrhea or other gastrointestinal symptoms. In 55-70% of cases, Listeria can affect the central nervous system (CNS)[6].  When Listeria spreads beyond the digestion tract, it can produce symptoms of headache, stiff neck, confusion, loss of balance, convulsions, meningitis, septicemia, and death[7]. Some immune compromised patients may not have any symptoms. Listeria employs multiple methods to spread through unsuspecting people.

Listeria uses multiple methods to help it to spread through the body
The first line of defense against food borne Listeria are the endothelial cells which line the intestines. Listeria employs multiple strategies to invade several different types of cells and spread through the body: intestinal epithelial cells, hepatocytes, placental cytotrophoblasts, endothelial cells, macrophages and other immune cells[8]. In one lab study, listeriolysin O (LLO) is a toxin produced by Listeria which enables it to move freely inside of and to propagate between endothelial cells[9]. This toxin also disables “T” cells which enable this bacteria to evade the immune system and survive longer[10]. Listeria has also developed drug resistance to multiple antibiotics.

Listeria can persist due to drug resistance to many antibiotics
Unfortunately, mutant strains of Listeria have developed resistance to several antibiotics including: ampicillin, cephalothin, penicillin, meticillin, oxacillin[11],  tetracycline, streptomycin, cefotaxime, and gentamicin[12]. Listeria uses a mechanism called an effux pump to sample drug molecules to develop drug-resistance[13]. This bacteria can also produce biofilms under which many species of pathogens may live, which suggests that Listeria is likely capable of long-term infection in the gut[14]. In one study on sanitizers, Listeria under a biofilm demonstrated increased resistance of 1000 times[15]. In another lab study, Listeria has also been shown to be capable of receiving drug resistant genes from other bacteria that contaminate food[16]. Unfortunately, some Lyme disease patients with chronic digestion problems have tested positive for resonant frequencies for Listeria in their intestines.

What else can help people with Lyme disease to fight a drug-resistant, biofilm forming, intracellular Listeria gut and central nervous system infection?

Here are five strategies for stopping Listeria infections in the gut and the central nervous system
Here are four strategies for helping to stop Listeria from spreading. Making remedies into a small particle size can increase their anti-Listeria properties. When anti-Listeria medicines were processed into small particles and wrapped with a lipid or a fat outer layer called a liposome, they had a 90-fold greater effect at killing the intracellular infection in mice[17]. Liposomal remedies have been shown to be more effective at penetrating and delivering remedies into Listeria infected cells than their non-liposomal equivalents[18]. In other studies, herbs, specific frequencies of light, and dietary changes inhibited Listeria.

Listeria Stopping Strategy #1: Essential Oils
In one lab study, five plant essential oils: bay, clove, cinnamon, nutmeg and thyme significantly reduced the toxin listeriolysin O[19], which can help to prevent Listeria monocytogenes from spreading through the body. In another lab study, nanoemulsions of anise oil were more effective at inhibiting Listeria than anise essential oil[20]. Other lab studies indicated the effectiveness of oregano[21], lemongrass[22], spearmint[23], clove[24], myrtle[25], ajowan[26], orange[27], peppermint[28], geranium[29], artemisia annua[30], cinnamon Chinese cassia, red thyme[31], lemon and cinnamon[32] essential oils against Listeria monocytogenes. In lab experiments, thyme and oregano[33] essential oils were also effective at eliminating the biofilm forms of Listeria. Encapsulation the oils in liposomes, increases their effectiveness at targeting intracellular L. monocytogenes in endothelial cells[34] and the central nervous system[35]. Not only oils can help with stopping Listeria, so can specific wavelengths of light.

Listeria Stopping Strategy #2: Light Therapy
Light Emitting Diode (LED) frequencies of 405 nm[36] and 461 nm[37] inactivated L. monocytogenes in multiple lab experiments. Applying these wavelengths to the skin may help with stopping a cutaneous Listeria[38] infection. In studies on the penetration depth of laser wavelengths of 405 nm, this frequency was able to penetrate to a depth of 0.08 mm with 55% transmission into fair colored skin, and 2.5% in darker skin[39]. In addition to light, herbs can also help with stopping Listeria.

Listeria Stopping Strategy #3: Herbs
In addition to essential oils and light frequencies, these herb extracts have anti-Listeria properties in one study: rosemary, Echinacea angustifolia, thyme, tea tree, and peppermint[40]. In other studies, green tea was effective at inhibiting Listeria in food[41]. A green tea compound called epigallocatechin gallate (ECGC) was also effective at inhibiting the intracellular growth of L. Monocytogenes in a macrophage study[42]. Processing these herbs into small particle liposomes enhances their ability to penetrate and stop intracellular Listeria[43] and potentially disrupt it’s biofilms[44]. Not only herbs, but also tiny electrical frequencies can help to stop a Listeria infection.

Listeria Stopping Strategy #4: Frequency Specific Microcurrent
Frequency Specific Microcurrent uses millionth of an amp electrical currents to reduce bacterial infections, toxins and inflammation[45]. Frequencies for reducing pathogens, neutralizing toxins and inflammation, and promoting healing are combined with frequencies to target Listeria hiding inside blood cells[46], and organs like the intestines[47], liver, spleen[48], and the central nervous system[49]. These paired frequencies have been helpful in reducing symptoms in patients with meningitis, headaches, and confusion. In addition to microcurrent, dietary changes can also help to fight Listeria.

Listeria Stopping Strategy #5: Dietary Changes
In multiple studies, these foods and supplements inhibited the growth of Listeria: virgin olive oil[50], zinc and isomeric vitamin A[51], feijoa fruit extract from New Zealand[52], Lactobacilus[53] and Bifidobacterium[54] probiotics. Eliminating alcohol intake may also help with boosting the strength of your innate immunity against Listeria[55]. Multiple strategies can help people with Lyme to stop a persistent Listeria gut or brain infection.

A combination of anti-Listeria strategies can help to resolve a chronic gastrointestinal problems or infections in people with Lyme disease
Similar to taking the hitchhiking seeds off your clothes, anti-Listeria remedies and treatments may help to resolve chronic digestion problem, gut infections and meningitis. Processing these oils and herbs into a small particle liposome can enhance their antimicrobial, antibiofilm properties, and ability to penetrate inside cells and into the central nervous system. Some patients will also take these oils or herb extracts in an enema to increase their delivery into the intestines. Since some of these oils and herbs have cautions on their use, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

Next step: Come to the Getting Rid of Lyme Disease evening lecture on Monday June 6th at 6pm in Frederick, Maryland to learn more about essential oils, herbs, and treatments for healing from Lyme disease and co-infection symptoms.

https://goodbyelyme.com/events/get_rid_lyme

Also learn about effective remedies and treatments for relieving persistent symptoms of Lyme and co-infections including: cold laser, Frequency Specific Microcurrent, cupping, LED therapy, moxabustion, acupuncture, liposomal herbs, essential oils, bee venom, and more!

P.S. Do you have experiences where remedies or treatments helped you to overcome chronic gut problems caused by a toxic Listeria infection? Tell us about it.

[1] “Multistate Outbreak of Listeriosis Linked to Whole Cantaloupes from Jensen Farms, Colorado | Listeria | CDC.” Accessed May 21, 2016. https://www.cdc.gov/listeria/outbreaks/cantaloupes-jensen-farms/index.html.

[2] “Vital Signs: Listeria Illnesses, Deaths, and Outbreaks — United States, 2009–2011.” Accessed May 21, 2016. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6222a4.htm.

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[4] Vázquez-Boland, et al. “Listeria Pathogenesis and Molecular Virulence Determinants.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC88991/#

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[7] “Definition & Symptoms | Listeria | CDC.” Accessed May 21, 2016. https://www.cdc.gov/listeria/definition.html.

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Why You Need These Four Essential Oils for Relieving Lyme Disease Insomnia and Brain Fog caused by Toxic Sinuses

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Ernie_Banks_gum

For people with Lyme disease who have brain fog and insomnia due to toxic sinus infections
by Greg Lee

 

I loved collecting baseball cards as a kid. When I opened a new pack of cards, I was always filled with excited thoughts of, “Will I get a Willie Mays or a Hank Aaron?” And sometimes I only got cards that I already had multiple copies of, bless you Bob Burda. After finding out which cards I received, I got to enjoy a big pink stick of bubble gum. I got in big trouble once, when I put the gum in my pocket and it ended up going through the washer. Many of the other clothes ended up being stuck to pink gooey gum.

 

How is melted bubble gum that sticks to your clothes similar to toxic sinus infections in people with Lyme?

 

Just like gooey bubble gum, toxic infections can get stuck in the sinuses
In multiple studies, people with chronic sinus irritation have tested positive for a variety of different infections including: Staphylococcus aureus[1], Staphylococcus epidermidis[2], Streptococcus intermedius[3], Chlamydia[4], Clostridia[5], Mycoplasma[6], Nocardia nova[7], Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pyogenes, and anaerobic organisms: Prevotella and Porphyromonas, Fusobacterium, and Peptostreptococcus spp.[8] In immune compromised patients, multiple infections have detected including: Alternaria alternata[9], Aspergillus flavus[10], Mucormycetes[11], Fusarium[12], Cytomegalovirus[13], Bordetella petrii[14], Escherichia coli, Stenotrophomonas maltophilia, and basidiomycetous fungi (Schizophyllum commune)[15]. In rare cases, unusual infections that are mostly found in animals or soil have also been detected in sinus infections like: Staphylococcus pseudintermedius[16], and Paecilomyces variotii[17]. In other studies, dental infections have also been found to invade the sinuses[18]. Inflammatory markers can help to identify the types of infections in the sinus.

 

Inflammatory markers can give a clue to bacterial and fungal sinus infections
In sinus patients infected with Aspergillus and Alternaria, interleukin (IL)- 2, IL-4, IL-5, IL-10, tumor necrosis factor α, and interferon-γ were elevated[19]. Another study on chronic bacterial sinus infection patients showed that inflammatory markers IL-4, IL-8, IL-13 and Myeloperoxidase (MPO) were higher in the upper airway compared to the lower airway[20]. Sinus infections can also produce chronic physical problems and difficult emotions.

 

Sinus infections can affect physical as well as emotional symptoms
Severe sinus infections produce toxins which triggers inflammation and can lead to complications like irritability, decreased attention, anxiety, insomnia, depression[21], meningitis, abscesses in the brain[22], paralysis, tremors, weakness, blindness[23], sepsis[24], cerebral aneurysm[25], stroke[26], and death[27]. Elevated inflammatory compounds: IL-1β, IL-6, IL-8, and IL-13 were correlated with sleep disturbance and depression and may be an indicator of the severity of a sinus infection[28]. Unfortunately, these infections have multiple defense mechanisms to help them persist in the sinuses.

 

Toxic sinus infections can survive longer by hiding under multiple defenses
Sinus infections can be characterized by local inflammation, mucus discharge, immunoglobulin deficiency[29], pus, cysts, or polyps[30]. Sinus polyps have been found to have high levels of fibrin[31], which can isolate infections from your immune system and medications. Biofilms[32] are a slime produced by many different infections to protect against antimicrobial drugs, the killer cells of the immune system, and against other pathogens. Biofilms can increase drug resistance by a factor of ten to a thousand fold[33]. Biofilms are believed to be a main cause of recurring sinus infections that persist despite surgeries, multiple rounds of antibiotics or antifungals[34]. One study identifies nasal cysts, polyps, and mucus as likely places where infections can survive despite intravenous antibiotic treatment[35]. Unfortunately, patients with Lyme disease have also been found to have drug-resistant Staph bacteria.

 

Drug resistant Staph bacterial have been detected in the sinuses of Lyme patients receiving antibiotic treatment
Dr. Ritchie Shoemaker has found Multiple Antibiotic Resistant Coagulase Negative Staph (MARCoNS) infections in the sinuses of his patients receiving antibiotic treatment[36]. His protocol uses a nasal spray consisting of antibiotics along with biofilm dissolving EDTA. Unfortunately, the majority of health care providers treating Lyme patients are not following Dr. Shoemaker’s protocol.

 

What else can help people with Lyme disease to fight drug-resistant, biofilm forming, multi-species sinus infections?

 

Here are four essential oils that are effective at inhibiting infections and inflammatory compounds found in sinus infections
Fortunately, there are essential oils that have been found to inhibit many of the infections and biofilms that infect the sinuses and have also been effective at relieving pain, sleep problems, and difficult emotions. Preparing the remedies in a micronized form called a liposome, which are microscopic particles of medicinal oils that are wrapped in a lipid, increases their penetration into tissues and their antimicrobial, antibiofilm properties[37]. Which is why liposomal remedies may be highly effective at helping patients with penetrating into and eliminating persistent sinus infections and accompanying symptoms.

 

Sinus Infection Essential Oil #1: Tea Tree
In one wound study, liposomal tea tree oil combined with silver ions was effective at inhibiting Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans[38]. Tea Tree essential oil was also effective a reducing the size of wounds caused by methicillin-resistant Staphylococcus aureus (MRSA)[39]. Tea tree oil was also effective against Staphylococcus epidermidis, Escherichia coli, Saccharomyces cerevisiae[40], antibiotic resistant Candida spp.[41], Pseudomonas aeruginosa and its biofilm,[42] Aspergillus niger, Aspergillus flavus[43], Aspergillus fumigatus, Penicillium chrysogenum[44], Mycoplasma pneumoniae, Mycoplasma hominis and Mycoplasma fermentans[45], group A streptococcus[46], Fusarium graminearum, Fusarium culmorum, Pyrenophora graminea[47], Alternaria alternata, Botrytis cinerea and Fusarium oxysporum[48] in lab and animal studies.

 

In response to bacterial endotoxins, tea tree essential oil was effective at lowering inflammatory compounds IL-1β, IL-6 and IL-10[49]. In another lab study, tea tree oil decreased IL-2 and increased anti-inflammatory compound IL-4[50]. Caution: some cases have been reported where tea tree oil caused allergic dermatitis when placed on the skin[51]. In five cases, high doses of this oil internally, 0.5-1.0 ml/kg, have produced central nervous system symptoms of loss of coordination, drowsiness, unconsciousness, diarrhea, and abdominal pain[52]. In addition to tea tree oil, cinnamon has excellent antimicrobial properties.

 

Sinus Infection Essential Oil #2: Cinnamon Bark 
In unpublished lab research, cinnamon essential oil was effective at cutting through the Lyme biofilm and killing the bacteria. This oil is also effective at inhibiting: multi-drug resistant Pseudomonas aeruginosa and Escherichia coli toxin production and biofilms[53], multi-drug resistant strains of Salmonella typhi, Salmonella paratyphi A, Escherichia coli, Staphylococcus aureus, Pseudomonas fluorescens and Bacillus licheniformis[54], methicillin-resistant Staphylococcus aureus (MRSA)[55], Candida albicans[56], quorum sensing communication in drug resistant Chromobacterium violaceum and Pseudomonas aeruginosa[57], Haemophilus influenzae, Streptococcus pneumoniae, Streptococcus pyogenes[58], Campylobacter jejuni, Salmonella enteritidis, Listeria monocytogenes[59], Penicillium commune, P. roqueforti, Aspergillus flavus and Endomyces fibuliger[60].

 

In other studies which combine this oil and antibiotics, cinnamon bark essential oil helped to reduce drug resistance in multiple bacterial strains when combined with a beta-lactam antibiotic[61] and had a synergistic effect with gentamicin against multidrug-resistant Acinetobacter spp.[62]. Cinnamon oil has produced allergic dermatitis in some cases when placed on the skin. This oil may interfere with blood clotting. In one case, a boy drank 60 ml of cinnamon oil upon a dare and experienced symptoms of burning sensation in the mouth, chest and stomach, dizziness, double vision, nausea, vomiting and later collapse[63]. Another promising sinus antimicrobial remedy is thyme oil.

 

Sinus Infection Essential Oil #3: Thyme 
Thyme essential oil has been shown to inhibit Methicillin resistant Staphylococcus aureus (MRSA)[64], Staphylococcus aureus biofilms[65], Antibiotic-Resistant Candida spp.[66], Vancomycin-Resistant Enterococci[67], drug-resistant strains of Aspergillus spp. and Trichophyton rubrum[68],  Clostridium perfringens, Campylobacter jejuni[69], Listeria monocytogenes, Salmonella Typhimurium, enterohemorrhagic Escherichia coli, Brochothrix thermosphacta, Pseudomonas fluorescens[70], Zygosaccharomyces bailii[71], Staphylococcus, Enterococcus, Escherichia, Pseudomonas genera[72], Aeromonas species[73], Haemophilus influenzae, Streptococcus pneumoniae, and Streptococcus pyogenes[74].

 

In one mouse colitis experiment, thyme oil combined with oregano essential oil was effective at lowering IL-1beta, IL-6, GM-CSF, and TNFalpha[75]. Caution: thyme oil (geraniol chemotype) should not be taken in people with obstructed bile flow[76]. In addition to thyme, lemongrass has antimicrobial and antibiofilm properties.

 

Sinus Infection Essential Oil #4: Lemongrass 
Lemongrass essential oil has inhibited Staphylococcus aureus biofilms[77], drug-resistant strains of Actinomyces naeslundii, Porphyromonas gingivalis[78], methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), multi-drug resistant Pseudomonas aeruginosa, ESBL-producing Escherichia coli, Klebsiella pneumoniae[79], multi-drug resistant Candida albicans[80], multi-drug resistant strains of Streptococcus and Candida[81], and the Aeromonas hydrophyla biofilm[82].

 

Vaporized lemongrass oil combined with geranium oil inhibited MRSA, vancomycin-resistant Enterococci (VRE), Acinetobacter baumanii and Clostridium difficile[83]. Lemongrass oil followed by clove oil was highly effective against Candida albicans and its biofilms[84]. In one lab study, lemongrass oil inhibited the production of IL-1beta and IL-6[85]. Using multiple essential oils in combination can help with reducing chronic sinus infection symptoms.

 

Essential oils in combination can help to resolve chronic sinus infection symptoms in people with Lyme
Similar to getting sticky bubble gum off a bunch of clothes, essential oils can help people with Lyme to reduce sinus infection symptoms. Combining these oils can enhance their antimicrobial and antibiofilm properties. Patients that take these oils in a carrier oil under their tongue report reduced inflammation, improved sleep, and less brain fog. When encapsulated into a micronized particle called a liposome, these oils may be capable of even greater penetration into the sinus tissues when held in the mouth. In addition to inhibiting multiple harmful bacteria and fungi, these oils may also help with relieving uncomfortable emotions that are associated with elevated toxins and inflammation. Since some of these essential oils have cautions on their use, work with a Lyme literate essential oil practitioner to develop a proper, safe, and effective strategy for your condition.

 

– Greg

Next step: Come to the Getting Rid of Lyme Disease evening lecture on Monday June 6th at 6pm in Frederick, Maryland to learn more about essential oils, herbs, and treatments for healing from Lyme disease and co-infection symptoms.

https://goodbyelyme.com/events/get_rid_lyme

Also learn about effective remedies and treatments for relieving persistent symptoms of Lyme and co-infections including: cold laser, Frequency Specific Microcurrent, cupping, LED therapy, moxabustion, acupuncture, liposomal herbs, essential oils, bee venom, and more!

P.S. Do you have experiences where remedies or treatments helped you to overcome insomnia and brain fog caused by a toxic sinus infection? Tell us about it.

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