Monthly Archives: July 2016

How These Four Herbs Help to Stop Bartonella Rage and Obsessive Compulsive Disorder (OCD)

For people who have been diagnosed with Bartonella that have severe anger and obsessive compulsive behaviors
by Greg Lee

A few months ago I got a surprise call from my credit card provider who asked if I had made a recent $900 purchase from a clothing store in New York. I told them that I didn’t. They also asked about other charges made in shops and restaurants in the same area. Somehow my credit card number was stolen and being used. Several charges had accumulated in a short period of time before the card was canceled.

How is a thief that buys stuff on your credit card just like anger and obsessive behaviors caused by a Bartonella infection?

Just like fraudulent credit card charges that are made without your knowledge, Bartonella can quietly infect organs and tissues throughout the body

Bartonella is a Gram-negative bacterial infection that can be transmitted by insect bites, including fleas, lice, sand flies[1], flea feces,[2] mites[3], and possibly by ticks[4], spiders[5], or bed bugs[6]. This infection may also be transmitted by infected animal bites[7], scratches[8], or possibly by blood transfusion[9] or organ transplant[10].  There are over thirty species of Bartonella, and seventeen of these can infect humans[11]. This bacteria has been found to infect the liver, lymph nodes, skin[12], teeth[13], bones, heart, spleen, eyes, kidney, and brain[14]. This infection manipulates the circulatory system to spread through the body.

Bartonella stimulates the production of vascular endothelial growth factor (VEGF) to invade the body

VEGF is produced in the body to stimulate the production of new blood vessels[15]. In one study that looked at two species of Bartonella henselae, genotype I, aka Houston-1, and II, aka Marseille strain, genotype I was more virulent in human cells due to it’s ability to increase VEGF production and it’s receptor VEGFR-2 in human microvascular endothelial cells[16]. As new blood vessels grow due to VEGF production, Bartonella is then able to infect and spread through the endothelial cell lining of these new vessels[17]. Antibiotics are often the first course of treatment.

Antibiotics are highly effective in killing Bartonella in the lab but not as effective in people

In multiple lab studies, Bartonella was successfully eliminated using these antibiotics: amoxycillin and ceftriaxone, aminoglycosides, doxycycline, rifampicin, erythromycin doxycycline, and ciprofloxacin[18]. However, treatment failures and relapses have been reported with rifampin, ciprofloxacin, gentamicin, co-trimoxazole, and azithromycin[19]. One reason for these failures may be due to resistant strains of Bartonella to antibiotics: quinolones[20], rifampin[21], macrolides[22], fluoroquinolones[23], and gentamicin[24]. Another reason for antibiotic treatment failure may be due to this bacterias ability to produce or to hide within a protective slime called a biofilm. In one study, B. quintana was discovered in a exopolysaccharide (EPS)-like matrix, i.e. bioflm, in lice feces[25]. Biofilms are believed to increase drug resistance up to a thousand times[26]. This infection can produce a wide variety of physical and emotional symptoms.

Bartonella can produce many symptoms including anger, rage and obsessive compulsive disorder (OCD) behaviors
A Bartonella infection can produce symptoms of anemia[27], frequent headaches, visual and auditory hallucinations, anxiety, vision loss, paralysis, facial palsy, chronic insomnia, seizures, dizziness, cognitive dysfunction, and memory loss[28]. It has been found to mimic symptoms of multiple sclerosis (MS)[29], stroke[30], vasculitis[31], breast tumors, pancreatic, biliary or pharyngeal cancer[32], and rheumatic disease[33]. One Lyme literate specialist reports anger, rage and obsessive compulsive behavior in her Bartonella patients[34]. Obsessive behavior may be associated with a reaction in a specific area of the brain.

A specific region of the brain called the basal ganglia is associated with obsessive compulsive behavior

Obsessive compulsive behaviors are a signature symptom in children diagnosed with Pediatric Autoimmune Disorders Associated with Strep (PANDAS). In children with PANDAs, an infection by group A beta-hemolytic streptococcus (GABHS), toxins, or inflammation stimulates an autoimmune reaction in the basal ganglia area of the brain[35]. This reaction produces obsessive compulsive disorder (OCD) behaviors[36]. In one study, 19% of Bartonella patients showed lesions on brain MRIs in the cerebral white matter, basal ganglia, thalamus, and gray matter[37]. If Bartonella can produce abnormal MRI lesions in the basal ganglia, then it may be capable of producing OCD behaviors similar to a PANDAS infection.

What else can help you to stop a resistant Bartonella infection that produces angry outbursts, rage, or obsessive compulsive behaviors?

In Chinese medicine, anger, rage, and compulsive behaviors are associated with an imbalance in the liver

In Chinese medicine, when the liver becomes too hot or too dry due to excess toxins, a person may exhibit symptoms of sudden anger or rage[38]. A Chinese medicine diagnosis of liver stagnation, also known as congestion, along with a spleen deficiency is associated with OCD behaviors[39]. Obsessive compulsive behaviors have also been identified in people with toxic parasitic infections called Gu Syndrome in Chinese medicine texts[40]. Some patients with obsessive behaviors report a need to have their environment in a precise order by putting things in a specific place, extreme anxiety over unexpected surprises that disrupt daily rituals, or thoughts like, “Did I lock the door?” that they worry about over and over again. Fortunately, there are four herbs which may help to reduce obsessive behaviors, inhibit VEGF production, and lower rage by cooling and moistening the liver.

Here are four herbs for stopping Bartonella from spreading and causing painful emotions

Limiting VEGF production may help to stop Bartonella from spreading. Harmonizing the liver is a Chinese medicine strategy for lowering rage and obsessive compulsive behaviors. Formulating remedies into microparticles called liposomes increases their penetration into endothelial cells[41] where Bartonella hides out, the liver[42], and the basal ganglia[43] Liposomal remedies have also been effective at reducing the production of VEGF[44] and its receptor VEGFR2[45], which may help to limit the virulence of Bartonella. These herbs have been used for centuries in traditional medicine formulas for treating angry outbursts, rage, and obsessive compulsive disorder (OCD) behavior.

Stopping Bartonella Rage and OCD Herb #1: Angelica sinensis

Angelica sinensis, Chinese name Dang Gui, has antimicrobial, neuro-protective, anticancer, anticoagulant, and liver-protective properties. In Chinese medicine, angelica is used to strengthen and replenish the blood and it’s used to treat anemia, pale complexion, dry hair, dizziness, blurred vision, fatigue and weakness, palpitations and pain[46]. It is a primary ingredient in multiple Chinese herbal formulas for reducing angry outbursts or rage due to a liver imbalance[47] called liver yin deficiency or liver fire blazing.

In a lab study, angelica was effective at reducing VEGF[48]. In another study, angelica was effective at increasing cognitive abilities and brain plasticity of rats when under chronic stress[49]. Angelica also has demonstrated anti-endotoxin properties in multiple animal studies[50]. This herb has demonstrated an inhibitory effect on Salmonella typhi, E. coli, Corynebacterium diptheriae, Vibrio cholerae, alpha-hemolytic streptococcus, and beta-hemolytic streptococcus[51]. Another herb that is often used with angelica is peony.

Stopping Bartonella Rage and OCD Herb #2: White peony root

White peony root, Chinese name Bai Shao, has anti-inflammatory, antibiotic, CNS calming, and digestion healing properties. In Chinese medicine, white peony is used to nourish the blood, treat anemia, regulate menstrual disorders, relieve pain, reduce night sweats, nourish, cool and soften the liver[52]. A compound found in white peony called total glucosides was effective in reducing the abnormal proliferation of VEGF in a rat study[53]. Paeoniflorin, another component of white peony, demonstrated liver protective[54] and anti-endotoxin[55] properties in multiple animal studies. Albiflorin, another compound in white peony, demonstrated similar anti-inflammatory properties compared to paeoniflorin[56].

This herb has shown to have an inhibitory effect against Bacillus dysenteriae, E. Coli, Salmonella typhi, Pseudonomas aeruginosa, Staphyloccus aureus, beta-hemolytic streptococcus, and Diplococcus pneumoniae[57]. Peony is often paired with angelica in herbal formulas for treating liver imbalances, including those that are marked by irritation, rage, and angry outbursts[58]. Bupleurum is another herb used in traditional Chinese medicine for supporting the liver.

Stopping Bartonella Rage and OCD Herb #3: Bupleurum

Bupleurum, Chinese name Chai Hu, has pathogen expelling, anti-malarial, liver harmonizing, and yang lifting properties. In Chinese medicine, bupleurum is used to treat infections with symptoms of fever, chills, fullness in the chest, bitter taste in the mouth, dry throat, poor appetite, nausea, vertigo, and irritability. This herb is often used to treat malaria, emotional distress, eye disorders, breast swelling and pain, irregular menstruation, jaundice, migraines, and prolapsed organs[59]. In Chinese herbal formulas, this herb is used to release anger and frustration that is inexpressible[60].

This herb has an inhibitory effect on B-hemolytic streptococcus, Vibrio cholerae, Mycobacterium tuberculosis, leptospirosis (a spirochete infection), influenza viruses, and hepatitus viruses Buplerum is cautioned in patients with excessive dryness and heat symptoms. There may an increased risk of acute pneumonitis when this herb is used with interferon[61]. Polysaccharides found in this herb have anti-toxin properties[62]. Bupleurum reduced depression in one human study by increasing Nerve Growth Factor (NGF) and Brain Derived Neurotrophic Factor (BDNF)[63]. In a rat study, an herbal formula with bupleurum was effective at reducing inflammatory cytokines causing jaundice and liver hepatitis[64]. Bupleurum is a component with angelica and white peony in a famous formula called “Rambling Powder” to treat liver stagnation[65]. Withania somnifera is another herb for calming the emotions.

Stopping Bartonella Rage and OCD Herb #4: Withania somnifera

Withania somnifera, also called ashwagandha, has a very revered place in ayurvedic medicine. It’s properties are tonifying, replenishing, longevity enhancing, adaptogenic, stress reducing, anti-tumor, neuroregenerative, anti-arthritic, aphrodisiac, narcotic, diuretic, anthelmintic, astringent, thermogenic, and stimulant[66].

Withania somnifera has been used to treat the following conditions: arthritis, inflammatory conditions, anxiety, insomnia, respiratory disorders, asthma, and bronchitis. It is also used to treat disorders of the nervous, immune, and the reproductive system. It is especially used to treat nervousness, depression, digestion problems, and low libido[67]. This herb has also been used to treat gastric ulcers, uterine fibroids, dementia, memory problems, Parkinson’s, Huntington’s, Alzheimer’s disease, mitochondrial energy depletion, rheumatoid, and osteoarthritis[68].

In one mouse study, Withania somnifera was effective at inhibiting obsessive compulsive behavior[69]. In a rat study, Withania somnifera demonstrated liver protective and anti-inflammatory effects against gentamicin liver damage[70]. This herb was also effective in multiple studies against Staphylococcus aureus, Methicilin Resistance Staphylococcus aureus (MRSA)[71], Enterococcus spp.[72], Escherichia coli, Salmonella typhi, Citrobacter freundii, Pseudomonas aeruginosa, Klebsiella pneumoniae[73], Aeromonas hydrophila[74], Plasmodium berghei[75], Linoleic and oleic acids from Withania somnifera were effective at inhibiting streptococcus mutans biofilms[76]. Withaferin A and withanone are compounds found in this herb that show inhibitiatory potential against leshmania protozoa[77]. Withaferin A also inhibited the production of H. pylori induced inflammatory compound IL-1beta[78], MMP-9[79] produced by metastatic cancer cells, and VEGF produced by brain cancer cells[80] in lab experiments. Using a combination of these herbs can help to fight the uncomfortable emotions triggered by a Bartonella infection.

These four herbs can help to reduce painful emotions of rage and obsessive compulsive behaviors from a Bartonella infection

People with Lyme disease that have uncontrolled anger, rage and obsessive behaviors may have a stealthy Bartonella infection affecting their liver and nervous system. Similar to canceling a credit card with fraudulent charges, these herbs may help to stop the spread of Bartonella through inhibiting VEGF. By harmonizing and decongesting the liver, these herbs may help to reduce angry outbursts and obsessive compulsive behaviors. Using liposomal anti-Bartonella herbs may be more effective in stopping Bartonella inside the liver, the basal ganglia in the brain, and in endothelial cells. Since some of these herbs have cautions on their use, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

Next step: Come to the Getting Rid of Lyme Disease evening lecture on Monday August 1st at 6pm in Frederick, Maryland to learn more about essential oils, herbs, and treatments for healing from Lyme disease and co-infection symptoms.

https://goodbyelyme.com/events/get_rid_lyme

Also learn about effective remedies and treatments for relieving persistent symptoms of Lyme and co-infections including: cold laser, Frequency Specific Microcurrent, cupping, LED therapy, moxabustion, acupuncture, liposomal herbs, essential oils, bee venom, and more!

P.S. Do you have experiences where remedies or treatments helped you to stop angry outbursts, rage, or obsessive compulsive behaviors due to a Bartonella infection? Tell us about it.


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[56]Wang, Qiang-Song, Teng Gao, Yuan-Lu Cui, Li-Na Gao, and Heng-Li Jiang. “Comparative Studies of Paeoniflorin and Albiflorin from Paeonia Lactiflora on Anti-Inflammatory Activities.” Pharmaceutical Biology 52, no. 9 (September 2014): 1189–95. doi:10.3109/13880209.2014.880490. https://www.ncbi.nlm.nih.gov/pubmed/24646307

[57]Chen, John K., and Tina T. Chen. Chinese Medical Herbology & Pharmacology. Edited by Laraine Crampton. 1st edition. City of Industry, Calif: Art of Medicine Press, 2004. p. 932.

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[62]Wu, Jian, Yun-Yi Zhang, Li Guo, Hong Li, and Dao-Feng Chen. “Bupleurum Polysaccharides Attenuates Lipopolysaccharide-Induced Inflammation via Modulating Toll-like Receptor 4 Signaling.” PloS One 8, no. 10 (2013): e78051. doi:10.1371/journal.pone.0078051. https://www.ncbi.nlm.nih.gov/pubmed/24167596

[63]Wang, Xia, Qing Feng, Yong Xiao, and Ping Li. “Radix Bupleuri Ameliorates Depression by Increasing Nerve Growth Factor and Brain-Derived Neurotrophic Factor.” International Journal of Clinical and Experimental Medicine 8, no. 6 (2015): 9205–17. https://www.ncbi.nlm.nih.gov/pubmed/26309578

[64]Lin, L., W. M. Cai, C. J. Qin, L. C. Miao, L. T. Yun, Y. Hua, and L. Weilin. “Intervention of TLR4 Signal Pathway Cytokines in Severe Liver Injury with Obstructive Jaundice in Rats.” International Journal of Sports Medicine 33, no. 7 (July 2012): 572–79. doi:10.1055/s-0031-1301318. Lin, L., W. M. Cai, C. J. Qin, L. C. Miao, L. T. Yun, Y. Hua, and L. Weilin. “Intervention of TLR4 Signal Pathway Cytokines in Severe Liver Injury with Obstructive Jaundice in Rats.” International Journal of Sports Medicine 33, no. 7 (July 2012): 572–79. doi:10.1055/s-0031-1301318. https://www.ncbi.nlm.nih.gov/pubmed/22562737

[65]Beau. “Psychospiritual Aspects of Herbal Medicine.” Accessed July 28, 2016. https://www.planetherbs.com/theory/psychospiritual-aspects-of-herbal-medicine.html.

[66]Singh, Narendra, Mohit Bhalla, Prashanti de Jager, and Marilena Gilca. “An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda.” African Journal of Traditional, Complementary, and Alternative Medicines 8, no. 5 Suppl (July 3, 2011): 208–13. doi:10.4314/ajtcam.v8i5S.9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/

[67]Beau. “Ashwagandha: Wonder Herb of India.” Accessed July 28, 2016. https://www.planetherbs.com/specific-herbs/ashwagandha-wonder-herb-of-india.html.

[68]Singh, Narendra, Mohit Bhalla, Prashanti de Jager, and Marilena Gilca. “An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda.” African Journal of Traditional, Complementary, and Alternative Medicines 8, no. 5 Suppl (July 3, 2011): 208–13. doi:10.4314/ajtcam.v8i5S.9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/

[69]Kaurav, Bhanu P. S., Manish M. Wanjari, Amol Chandekar, Nagendra Singh Chauhan, and Neeraj Upmanyu. “Influence of Withania Somnifera on Obsessive Compulsive Disorder in Mice.” Asian Pacific Journal of Tropical Medicine 5, no. 5 (May 2012): 380–84. doi:10.1016/S1995-7645(12)60063-7. https://www.ncbi.nlm.nih.gov/pubmed/22546655

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[71]Mwitari, Peter G., Peter A. Ayeka, Joyce Ondicho, Esther N. Matu, and Christine C. Bii. “Antimicrobial Activity and Probable Mechanisms of Action of Medicinal Plants of Kenya: Withania Somnifera, Warbugia Ugandensis, Prunus Africana and Plectrunthus Barbatus.” PLoS ONE 8, no. 6 (June 13, 2013). doi:10.1371/journal.pone.0065619. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681961/

[72]Bisht, Punum, and Vinita Rawat. “Antibacterial Activity of Withania Somnifera against Gram-Positive Isolates from Pus Samples.” Ayu 35, no. 3 (September 2014): 330–32. doi:10.4103/0974-8520.153757. https://www.ncbi.nlm.nih.gov/pubmed/25972723

[73]Alam, Nadia, Monzur Hossain, Md Abdul Mottalib, Siti Amrah Sulaiman, Siew Hua Gan, and Md Ibrahim Khalil. “Methanolic Extracts of Withania Somnifera Leaves, Fruits and Roots Possess Antioxidant Properties and Antibacterial Activities.” BMC Complementary and Alternative Medicine 12 (October 7, 2012): 175. doi:10.1186/1472-6882-12-175. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527235/

[74]Sharma, Arun, Ashutosh D. Deo, S. Tandel Riteshkumar, Thongam Ibemcha Chanu, and Arabinda Das. “Effect of Withania Somnifera (L. Dunal) Root as a Feed Additive on Immunological Parameters and Disease Resistance to Aeromonas Hydrophila in Labeo Rohita (Hamilton) Fingerlings.” Fish & Shellfish Immunology 29, no. 3 (September 2010): 508–12. doi:10.1016/j.fsi.2010.05.005. https://www.ncbi.nlm.nih.gov/pubmed/20580830

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[77]Grover, Abhinav, Shashank Prakash Katiyar, Jeyaraman Jeyakanthan, Vikash Kumar Dubey, and Durai Sundar. “Blocking Protein Kinase C Signaling Pathway: Mechanistic Insights into the Anti-Leishmanial Activity of Prospective Herbal Drugs from Withania Somnifera.” BMC Genomics 13 Suppl 7 (2012): S20. doi:10.1186/1471-2164-13-S7-S20. https://www.ncbi.nlm.nih.gov/pubmed/23281834

[78]Kim, Jae-Eun, Jun-Young Lee, Min-Jung Kang, Yu-Jin Jeong, Jin-A. Choi, Sang-Muk Oh, Kyung-Bok Lee, and Jong-Hwan Park. “Withaferin A Inhibits Helicobacter Pylori-Induced Production of IL-1β in Dendritic Cells by Regulating NF-κB and NLRP3 Inflammasome Activation.” Immune Network 15, no. 6 (December 2015): 269–77. doi:10.4110/in.2015.15.6.269. https://www.ncbi.nlm.nih.gov/pubmed/26770181

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Is Memory Loss Caused by Neurological Lyme Disease or Brain Eating Parasites?

wasp_nest

For people with neurological Lyme disease that have dementia, multiple sclerosis, or Alzheimer’s disease
by Greg Lee
.
One afternoon, I heard one of my daughters cry out with a huge scream after a wasp stung her arm. After she was taken care of, I got out my wasp fighting gear: electric bug zapper, thick gloves, hat, and a bottle of hair spray. You may be asking, “Why hair spray?” It sticks like glue to the wasp’s wings so they can’t fly and I don’t like pesticides. Once they hurt my girl, then it got personal and they had to go!

So it was me against over a dozen wasps. After zapping and spraying them into submission, I saw one of the wasps crawl into a slot between two deck boards. And then another wasp followed. I cautiously peered into the slot and saw the nest. I got out the garden hose and sprayed that nest until no wasp remained. Then I quickly pried it out and threw it down the sewer. Once the nest was gone, the rest got the message and didn’t return.

How is being stung by angry wasps defending their nest similar to nematodes that infect the brain?

Just like a wasp nest that swarms you, nematodes can infect and damage the brain
Recent research by Dr. Alan MacDonald has found worms called nematodes in autopsy brain tissue samples from patients with neurological Lyme disease who were also diagnosed with Multiple Sclerosis, dementia, brain tumors, and Alzheimer’s Disease[1]. Lyme disease bacteria were actually detected within some of the nematodes. Similar to how wasps can hide in their nest, Lyme bacteria can hide from antibiotic treatment when they are inside of larger parasitic worms. Unfortunately, nematodes have also been detected in ticks.

In deer ticks and lone star ticks, nematodes have been detected
In multiple tick studies, nematodes have been detected in lone star ticks found in Maryland[2] and Virginia[3], and in deer ticks from Connecticut[4]. Ticks are capable of transmitting nematodes when they feed on a host[5]. Other vectors that can transmit nematodes are mosquitoes and black flies[6]. Once they infect a host, adult nematodes mate and then release thousands of very small larva called “microfilariae” into the blood. Microfilariae circulate throughout the host and can end up in the nervous system[7]. These microfilariae evolve into larvae which can eat through the brain and can cause a wide range of symptoms.

Nematodes produce many symptoms when they infect the brain and spinal fluid
Larval nematodes in the nervous system can damage tissues and produce masses called granulomas. They can also cause fibrosis, blockages in cerebral blood vessels, or inflammation resulting in meningitis, encephalitis or localized inflammation[8], weakness, blurred vision, stomach flu[9], and even death. In a Taiwan study, patients infected with nematodes reported meningitis, brain inflammation, fever, vomiting, headache, and neuropathy. Two patients died from their infection. In some patients, nematodes were recovered from their cerebral-spinal fluid (CSF). Elevated levels of inflammatory markers vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), and matrix metalloproteinase 9 (MMP-9) were also detected in patient’s CSF fluid[10]. Research shows that nematodes can also manipulate the immune system response.

Nematodes produce compounds to deflect how the immune system attacks parasites
One research study on a nematode called B. Malayi, identified proteins that it releases to manipulate the immune response in favor of a parasitic infection[11]. Another study on a filarial nematode infection illustrated how these parasites inhibit the inflammatory response by the immune system[12]. In most cases, anti-parasitic medications are used to treat nematode infections in the nervous system.

Anti-parasitic medications help to kill nematode infections in the brain and spinal fluid
Anti-parasitic medications called antihelminthics are used to treat nematodes in the nervous system including: Mebendazole, Pyrantel pamoate, Thiabendazole, Diethylcarbamazine (DEC), Ivermectin[13], Moxidectin[14], and Alinia[15]. Ivermectin and moxidectin are the most widely administrated antihelminthic medications for nematode infections and unfortunately, their widespread and frequent use has led to high level of resistance to these drugs[16]. Ivermectin only kills the microfilariae, not the adult nematode[17]. DEC can worsen onchocercal nematode eye infections. In patients with a nematode infection called loiasis, DEC can cause serious adverse reactions, including encephalopathy and death, depending upon the density of the parasites. DEC is only available in the US from the CDC upon submitting positive lab results[18]. A mechanism within nematodes called a “drug effux pump” is believed to enable these parasites to develop drug resistance[19]. Killing nematodes can lead to significant Herxheimer reactions.

A symbiotic bacteria within nematodes is the source of Herxheimer toxins
Wolbachia is a symbiotic bacteria which enables normal development and fertility of nematodes[20]. Wolbachia belong to the order Rickettsiales and is closely related to Anaplasma, Ehrlichia and Rickettsia[21]. Fortunately, this bacteria does not infect people. When nematodes are killed off by anti-parasitic drugs, Wolbachia cannot survive without their host and are killed, which releases their endotoxins. Wolbachia toxins stimulate the production of pro-inflammatory compounds including tumor necrosis factor alpha (TNF)-alpha, Interleukin-1 (IL-1), and Interleukin-12 (IL-12)[22]. In an animal study, Wolbachia surface protein upregulated (IL)-1beta, IL-6, and tumor necrosis factor[23]. These endotoxins and inflammatory compounds can produce painful symptoms associated with a Herxheimer reaction. A combination of anti-parasitic and antibiotic medications is more effective at reducing adult and microfilariae forms of nematodes.

A combination of medications which kill both the adult and microfilariae forms is more effective
Recent drug strategies combine Ivermectin for microfilariae and doxycycline to kill Wolbachia which eventually kills the adult nematodes in the nervous system. This combination drug treatment is recommended for six weeks[24]. Another animal study combined DEC with liposomal doxycycline and liposomal rifampin resulting in significant increase in microfilariae die off and a marginal increase in the die off of adult nematodes[25]. Other studies demonstrate the inhibitory effect of anti-Rickettsia antibiotics like tetracycline, rifampin, and azithromyacin on adult nematodes[26].

What else can help people to expel brain-eating nematodes from their central nervous system who have persistent neurological Lyme disease, multiple sclerosis, dementia, brain tumors, or Alzheimer’s disease?

Here are four strategies for expelling brain-eating nematodes from the central nervous system
A combination of remedies for attacking both the adult and microfilariae forms is the most effective at reducing the overall numbers of parasites. Formulating remedies into microparticles called liposomes enhances the efficacy of anti-parasitic herbs and essential oils for killing the different life stages of nematodes[27] and possibly their symbiotic bacteria.

Clearing Brain-Eating Nematodes Strategy #1: Essential Oils
Essential oils have been found to inhibit different species of nematodes.

Thyme essential oil was effective at inhibiting Meloydogine javanica[28] and larvae from the Anisakis nematode[29]. Thyme essential oil was also effective against gram negative bacteria: Pseudomonas aeruginosa[30], Salmonella spp.[31], and E. Coli[32]. Thyme combined with oregano oil reduced mRNA levels of pro-inflammatory cytokines IL-1beta, IL-6, GM-CSF, and TNFalpha[33].

Palmarosa essential oil was effective against Caenorhabditis elegans[34] and Haemonchus contortus[35] in separate studies. This oil was also effective at inhibiting E. Coli[36] and Aspergillus fumigatus[37]. Palmarosa oil also reduced pro-inflammatory compounds TNF-α, IL-1β, and IL-8[38] and increased anti-inflammatory IL-10 in lab studies[39].

Clove bud essential oil was highly effective at reducing[40] Meloidogyne incognita egg hatch 50% and killing second stage juveniles (J2) as much as 100% in a lab study[41]. Eugenol, the primary compound in clove bud oil, in one rat study reduced expression of VEGF, MMP-2, and MMP-9[42], which are elevated in nematode infections. Processing these oils into a liposomal micronized form increases their penetration into the nervous system[43]. Adding nanoparticles of silver to liposomal oils may further enhance their anti-microbial properties.

Clearing Brain-Eating Nematodes Strategy #2: Nanoparticle Silver
In multiple lab studies, nanoparticles of silver were effective at reducing motility and killing microfilariae of Brugia malayi[44], demonstrated antifilarial activity against microfilaria of S. Cervi[45], disrupted metabolism of Caenorhabditis elegans[46], and killed most of Meloidogyne incognita[47]. Encapsulating nanoparticles of silver along with essential oils into a liposomal remedy may increase their anti-parasitic and anti-symbiotic bacterial properties. When nanoparticle silver is combined with tea tree essential oil into a liposome, their antimicrobial efficiency is enhanced against Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans[48]. Silver nanoparticles may reduce inflammation from nematodes by inhibiting IL-1beta and VEGF induced permeability as reported in a pig study[49] and reducing MMP-2 and MMP-9 in another rat study[50]. Herbs have also been effective for treating nematode infections for thousands of years.

Clearing Brain-Eating Nematodes Strategy #3: Herbs
In addition to essential oils and silver, herbs have been used for centuries for fighting nematode infections.

Andrographis, Chinese name Chuan Xin Lian, has been effective at inhibiting Haemonchus contortus[51], microfilaricidal activity against Dirofilaria immitis filarids[52], antifilarial activity against adult worms of subperiodic Brugia malayi[53], killing in vitro the microfilaria of Dipetalonema reconditum in dogs[54], and anthelmintic activity against Ascaris lumbricoides[55]. This herb is also used in Chinese medicine against leptospirosis, another spirochete infection[56]. Andrographis was also effective at reducing inflammatory compounds IL-1α, IL-1β, and IL-6 in a lab study[57]. A compound in Andrographis called andrographolide inhibits expression of inflammatory compounds MMP-2, IL-1beta[58] and VEGF[59] in lab studies.

Ajowan, ajwain, or Trachyspermum ammi has been effective against multiple species of nematodes in multiple studies. Methanolic extract of fruits of Trachyspermum ammi were effective against adult bovine filarial Setaria digitata worms and demonstrated macrofilaricidal activity and female worm sterility in vivo against B. Malayi[60].

Lantana camara is an ornamental shrub which is very hardy and is used medicinally through much of the world. This herb contains triterpenoids pomolic acid, lantanolic acid, lantoic acid, camarin, lantacin, camarinin, and ursolic acid which exhibited 100% mortality in 24 – 48 hours against the nematode Meloidogyne incognita[61]. In other studies, a lantana extract killed adult Brugia malayi nematodes and sterilized many of the surviving female worms, and demonstrated strong microfilaricidal and sterilization efficacy with mild macrofilaricidal action against Acanthocheilonema viteae[62]. Not only herbs, but also tiny electrical frequencies can help to stop nematodes that have infected the brain and spinal fluid.

Clearing Brain-Eating Nematodes Strategy #4: Frequency Specific Microcurrent
Frequency Specific Microcurrent uses millionth of an amp electrical currents to reduce parasitic and bacterial infections, toxins and inflammation[63]. Frequencies for inhibiting parasitic worms, symbiotic bacteria, neutralizing toxins and inflammation, reducing tumors, and promoting healing are paired with frequencies to target infected areas of the nervous system: the brain, forebrain, meninges, basal ganglia, spinal cord, spinal fluid, cranial nerves, and eyes[64]. These paired frequencies have also been helpful in reducing symptoms in patients diagnosed with multiple sclerosis, autism, brain inflammation, mold toxicity, and neurological Lyme disease. These four strategies may help people with neurological Lyme to stop an underlying parasitic nematode brain infection.

A combination of anti-parasitic remedies and treatments can help to overcome a chronic neurological Lyme and nematode infection
People diagnosed with multiple sclerosis, Alzheimer’s disease, dementia, or brain tumors may have hidden parasitic nematodes along with Lyme disease in their nervous system. Just like finding and eliminating the wasp nest, expelling parasitic nematodes that harbor Lyme bacteria may help to improve neurological symptoms and memory recall. Using liposomal anti-parasitic and anti-symbiotic bacteria remedies and treatments may be effective in eliminating larger parasites and the Lyme bacteria they contain.

Anti-toxin treatments and remedies may also help with reducing inflammatory compounds which may lower toxic Herxheimer pain and discomfort. Making these remedies into micronized liposomes enhances their delivery into the nervous system and may increase their anti-nematode effectiveness. Since some of these treatments and remedies require specialized training, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

Next step: Come to the Getting Rid of Lyme Disease evening lecture on Monday July 11th at 6pm in Frederick, Maryland to learn more about essential oils, herbs, and treatments for healing from Lyme disease and co-infection symptoms.

https://goodbyelyme.com/events/get_rid_lyme

Also learn about effective remedies and treatments for relieving persistent symptoms of Lyme and co-infections including: cold laser, Frequency Specific Microcurrent, cupping, LED therapy, moxabustion, acupuncture, liposomal herbs, essential oils, bee venom, and more!

P.S. Do you have experiences where remedies or treatments helped you to overcome memory problems caused by brain-eating parasites or a Lyme disease infection? Tell us about it.


[1] “Borrelia Dwells in Parasitic Nematodes in Glioma & Neurodegenerative Disease.” Dr. Paul Duray Research Fellowship Endowment Inc, May 14, 2016. https://durayresearch.wordpress.com/borrelia-dwells-in-parasitic-nematodes-in-neurodegenerative-disease/.

[2] Zhang, Xing, Douglas E. Norris, and Jason L. Rasgon. “Distribution and Molecular Characterization of Wolbachia Endosymbionts and Filarial Nematodes in Maryland Populations of the Lone Star Tick (Amblyomma Americanum).” FEMS Microbiology Ecology 77, no. 1 (July 2011): 50–56. doi:10.1111/j.1574-6941.2011.01089.x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118304/
[3] Henning, Tyler C., John M. Orr, Joshua D. Smith, Jorge R. Arias, Jason L. Rasgon, and Douglas E. Norris. “Discovery of Filarial Nematode DNA in Amblyomma Americanum in Northern Virginia.” Ticks and Tick-Borne Diseases 7, no. 2 (March 2016): 315–18. doi:10.1016/j.ttbdis.2015.11.007. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876860/
[4] Namrata, Pabbati, Jamie M. Miller, Madari Shilpa, Patlolla Raghavender Reddy, Cheryl Bandoski, Michael J. Rossi, and Eva Sapi. “Filarial Nematode Infection in Ixodes Scapularis Ticks Collected from Southern Connecticut.” Veterinary Sciences 1, no. 1 (May 12, 2014): 5–15. doi:10.3390/vetsci1010005. https://www.mdpi.com/2306-7381/1/1/5
[5] Balashov, Iu S. “[The interrelationships of ixodid ticks (Ixodidae) with the causative agents of transmissible vertebrate infections].” Parazitologiia 29, no. 5 (October 1995): 337–52. https://www.ncbi.nlm.nih.gov/pubmed/8524614
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