Two Frogs has moved into a larger office!

We are open at our new location inside the:

Frederick Innovative Technology Center (FITCI) at
4539 Metropolitan Court
Frederick, MD 21704

There are multiple visitor spaces (highlighted in yellow) across from the front entrance of the FITCI.
If all the visitor spaces are taken, you can park in any open parking space.

Here is what the lobby looks like:

Have a seat in the waiting area.

Tell the receptionist you are here to see Greg Lee.
Restrooms are right behind the reception desk.
Water is available upon request.

Question? Call us at 301-228-3764 or email at TwoFrogsHealingCenter@gmail.com.
We look forward to seeing you in our new space!

Thanks,

Greg

There is a significant overlap between symptoms of a systemic Candida and Lyme disease infection
A systemic Candida infection can produce similar symptoms as found in patients with Lyme disease. Symptoms which overlap are:

• Fever and chills⁷
• Chronic fatigue⁸
• Digestion pain, bloating, and nausea⁹
• Meningitis¹⁰
• Headache¹¹
• Arthritis¹²
• Heart arrhythmia¹³
• Cognitive decline and memory recall problems¹⁴
• ADHD¹⁵
• Depression¹⁶
• Urinary tract infections¹⁷
• Systemic inflammatory response¹⁸
• Seizures¹⁹
• Death²⁰

Not surprisingly, both Lyme and Candida can trigger the release of similar inflammatory compounds which are associated with increased symptoms.

Both Lyme and Candida infections can trigger the increase of multiple inflammatory compounds
Candida²¹ and Lyme disease²² infections have been shown to trigger the release of Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Interleukin-8 (IL-8)²³, and Interleukin-10 (IL-10)²⁴. IL-1β is implicated in patients with depression²⁵ and joint inflammation²⁶. IL-6 is strongly associated with rheumatoid arthritis²⁷, depression²⁸, hostility²⁹, fatigue³⁰, flu-like symptoms and fever³¹, and cognitive impairment³². IL-8 is implicated in patients with anxiety³³, meningitis³⁴, and spirochete (leptospira) induced liver inflammation³⁵. IL-10 is associated with irritable bowel disease³⁶ and fatigue³⁷. Unfortunately, these infections also employ other mechanisms to help them survive in their hosts.

Candida and Lyme employ multiple mechanisms to survive longer
Both infections are capable of hiding inside of cells³⁸, and infecting the brain³⁹. They can producing biofilms⁴⁰, which are a slime produced to protect against antimicrobial drugs⁴¹, the killer cells of the immune system, and against other pathogens. Biofilms can increase drug resistance by a factor of ten to a thousand fold⁴². Biofilms are believed to be a main cause of recurring Candida or Lyme disease symptoms that persist despite multiple rounds of antibiotics⁴³ or antifungal medications⁴⁴. In addition to increased resistance from biofilms, Candida has also developed intrinsic and acquired resistance to multiple antifungal drugs⁴⁵. In addition to biofilms, Lyme bacteria and Candida are capable of producing proteins that lower the activation of the complement immune response⁴⁶. The complement immune system is a primary coordinator of the innate and adaptive immune responses for killing invading pathogens⁴⁷.

What else can help people with Lyme disease to fight a drug-resistant, biofilm forming, immune system manipulating, systemic Candida infection?

Here are four essential oils that are effective at inhibiting stubborn Candida infections
Fortunately, there are essential oils that have been found to inhibit drug resistant Candida, cut through biofilms, and enhance the immune response to invading infections. Some of these oils also help with reducing inflammatory compounds that are elevated in a Lyme and Candida infection. Preparing the remedies in a micronized form called a liposome increases their antimicrobial and antibiofilm properties. High dose liposomal antifungal medications have been safe and effective at treating systemic Candida infections in premature infants⁴⁸. Since liposomes are so small and are surrounded by a lipid, they have a greater ability to penetrate into cells where these infections can hide. Which is why liposomal remedies may be highly effective at helping patients with eliminating a resistant Candida infection.

Anti-Candida Essential Oil #1: Eucalyptus Essential Oil
In multiple lab studies, eucalyptus essential oil was highly effective at inhibiting the growth of fluconazole resistant Candida biofilms⁴⁹, inhibited the growth of hospital acquired drug resistant strains of Candida⁵⁰ and inducing innate cell mediated immune response against infections⁵¹. In other studies, eucalyptus oil was effective in relieving post-operative pain⁵² and inhibiting nitric oxide inflammatory production⁵³. In addition to eucalyptus oil, cinnamon has excellent anti-Candida properties.

Anti-Candida Essential Oil #2: Cinnamon Bark Essential Oil
In multiple studies, cinnamon essential oil is effective at inhibiting Candida albicans⁵⁴, Candida biofilms⁵⁵, hospital acquired strains of Candida⁵⁶, respiratory tract Candida⁵⁷, and fluconazole-resistant Candida⁵⁸. When combined in a capsule with patchouli essential oil, 71% of patients infected with an intestinal infection of multiple species of Candida were cured⁵⁹. Liposomal cinnamon oil was effective at inhibiting drug resistant staphylococcus and it’s biofilms⁶⁰. Cinnamon oil was effective in lab studies at inhibiting these inflammatory compounds: neurological inducible nitric oxide synthase (iNOS), Cyclooxygenase-2 (COX-2) expression, and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) inflammation⁶¹. Caution: cinnamon oil has produced allergic dermatitis in some cases when placed on the skin. This oil may interfere with blood clotting. In one case, a boy drank 60 ml of cinnamon oil upon a dare and experienced symptoms of burning sensation in the mouth, chest and stomach, dizziness, double vision, nausea, vomiting and later collapsed⁶². Another promising anti-Candida essential oil is lemongrass.

Anti-Candida Essential Oil #3: Lemongrass Essential Oil
Vaporized Lemongrass oil was 100% effective at inhibiting Candida albicans in a lab study⁶³. In other studies, lemongrass essential oil inhibited multi-drug resistant Candida albicans⁶⁴, multi-drug resistant strains of Streptococcus and Candida⁶⁵, and multiple species of Candida⁶⁶. Lemongrass essential oil has an enhanced killing effect against two species of Candida when combined with silver ions⁶⁷. Lemongrass oil followed by clove oil was highly effective against Candida albicans and its biofilms⁶⁸. In one lab study, lemongrass oil inhibited the production of IL-1beta and IL-6⁶⁹. In a human study, lemongrass oil reduced anxiety and tension⁷⁰. Another spice oil with anti-Candida properties is oregano.

Anti-Candida Essential Oil #4: Oregano Essential Oil
In multiple studies, oregano essential oil was highly effective at inhibiting multiple drug resistant species of Candida⁷¹, stopping germination and mycelial growth of Candida albicans in a dose dependent manner⁷², and inducing cell wall and membrane damage in thirty different strains of Candida albicans⁷³. Oregano oil inhibited IL-1beta, IL-6, GM-CSF, and TNF-alpha inflammatory compounds in a mouse experiment⁷⁴. Using multiple essential oils in combination can help with reducing systemic Candida infection symptoms and inflammation.

Essential oils in combination can help to resolve systemic Candida infection symptoms in people with Lyme
Similar to clearing out a tangled mass of ivy, essential oils can help people with Lyme to weed out systemic Candida symptoms. Combining these oils together may enhance their anti-Candia and anti-biofilm properties. Patients that have taken these oils combined with a carrier oil under their tongue have reported reduced symptoms of inflammation, improved sleep, and less brain fog.

When encapsulated into a micronized particle called a liposome, these oils may be capable of even greater penetration into the cells, nervous system, and into biofilms where Candida can hide. Through inhibiting the production of inflammatory compounds, these oils may also help with relieving physical symptoms and uncomfortable emotions that are associated with Candida toxins and inflammation. Since some of these essential oils have cautions on their use, work with a Lyme literate essential oil practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

Image courtesy: By KENPEI (KENPEI’s photo) [GFDL (https://www.gnu.org/copyleft/fdl.html), CC-BY-SA-3.0 (https://creativecommons.org/licenses/by-sa/3.0/) or CC BY-SA 2.1 jp (https://creativecommons.org/licenses/by-sa/2.1/jp/deed.en)], via Wikimedia Commons

Bartonella is a Gram-negative bacterial infection that can be transmitted by insect bites, including fleas, lice, sand flies^[1], flea feces,^[2] mites^[3], and possibly by ticks^[4], spiders^[5], or bed bugs^[6]. This infection may also be transmitted by infected animal bites^[7], scratches^[8], or possibly by blood transfusion^[9] or organ transplant^[10].  There are over thirty species of Bartonella, and seventeen of these can infect humans^[11]. This bacteria has been found to infect the liver, lymph nodes, skin^[12], teeth^[13], bones, heart, spleen, eyes, kidney, and brain^[14]. This infection manipulates the circulatory system to spread through the body.

VEGF is produced in the body to stimulate the production of new blood vessels^[15]. In one study that looked at two species of Bartonella henselae, genotype I, aka Houston-1, and II, aka Marseille strain, genotype I was more virulent in human cells due to it’s ability to increase VEGF production and it’s receptor VEGFR-2 in human microvascular endothelial cells^[16]. As new blood vessels grow due to VEGF production, Bartonella is then able to infect and spread through the endothelial cell lining of these new vessels^[17]. Antibiotics are often the first course of treatment.

In multiple lab studies, Bartonella was successfully eliminated using these antibiotics: amoxycillin and ceftriaxone, aminoglycosides, doxycycline, rifampicin, erythromycin doxycycline, and ciprofloxacin^[18]. However, treatment failures and relapses have been reported with rifampin, ciprofloxacin, gentamicin, co-trimoxazole, and azithromycin^[19]. One reason for these failures may be due to resistant strains of Bartonella to antibiotics: quinolones^[20], rifampin^[21], macrolides^[22], fluoroquinolones^[23], and gentamicin^[24]. Another reason for antibiotic treatment failure may be due to this bacterias ability to produce or to hide within a protective slime called a biofilm. In one study, B. quintana was discovered in a exopolysaccharide (EPS)-like matrix, i.e. bioflm, in lice feces^[25]. Biofilms are believed to increase drug resistance up to a thousand times^[26]. This infection can produce a wide variety of physical and emotional symptoms.

Bartonella can produce many symptoms including anger, rage and obsessive compulsive disorder (OCD) behaviors
A Bartonella infection can produce symptoms of anemia^[27], frequent headaches, visual and auditory hallucinations, anxiety, vision loss, paralysis, facial palsy, chronic insomnia, seizures, dizziness, cognitive dysfunction, and memory loss^[28]. It has been found to mimic symptoms of multiple sclerosis (MS)^[29], stroke^[30], vasculitis^[31], breast tumors, pancreatic, biliary or pharyngeal cancer^[32], and rheumatic disease^[33]. One Lyme literate specialist reports anger, rage and obsessive compulsive behavior in her Bartonella patients^[34]. Obsessive behavior may be associated with a reaction in a specific area of the brain.

Obsessive compulsive behaviors are a signature symptom in children diagnosed with Pediatric Autoimmune Disorders Associated with Strep (PANDAS). In children with PANDAs, an infection by group A beta-hemolytic streptococcus (GABHS), toxins, or inflammation stimulates an autoimmune reaction in the basal ganglia area of the brain^[35]. This reaction produces obsessive compulsive disorder (OCD) behaviors^[36]. In one study, 19% of Bartonella patients showed lesions on brain MRIs in the cerebral white matter, basal ganglia, thalamus, and gray matter^[37]. If Bartonella can produce abnormal MRI lesions in the basal ganglia, then it may be capable of producing OCD behaviors similar to a PANDAS infection.

What else can help you to stop a resistant Bartonella infection that produces angry outbursts, rage, or obsessive compulsive behaviors?

In Chinese medicine, when the liver becomes too hot or too dry due to excess toxins, a person may exhibit symptoms of sudden anger or rage^[38]. A Chinese medicine diagnosis of liver stagnation, also known as congestion, along with a spleen deficiency is associated with OCD behaviors^[39]. Obsessive compulsive behaviors have also been identified in people with toxic parasitic infections called Gu Syndrome in Chinese medicine texts^[40]. Some patients with obsessive behaviors report a need to have their environment in a precise order by putting things in a specific place, extreme anxiety over unexpected surprises that disrupt daily rituals, or thoughts like, “Did I lock the door?” that they worry about over and over again. Fortunately, there are four herbs which may help to reduce obsessive behaviors, inhibit VEGF production, and lower rage by cooling and moistening the liver.

Limiting VEGF production may help to stop Bartonella from spreading. Harmonizing the liver is a Chinese medicine strategy for lowering rage and obsessive compulsive behaviors. Formulating remedies into microparticles called liposomes increases their penetration into endothelial cells^[41] where Bartonella hides out, the liver^[42], and the basal ganglia^[43] Liposomal remedies have also been effective at reducing the production of VEGF^[44] and its receptor VEGFR2^[45], which may help to limit the virulence of Bartonella. These herbs have been used for centuries in traditional medicine formulas for treating angry outbursts, rage, and obsessive compulsive disorder (OCD) behavior.

Angelica sinensis, Chinese name Dang Gui, has antimicrobial, neuro-protective, anticancer, anticoagulant, and liver-protective properties. In Chinese medicine, angelica is used to strengthen and replenish the blood and it’s used to treat anemia, pale complexion, dry hair, dizziness, blurred vision, fatigue and weakness, palpitations and pain^[46]. It is a primary ingredient in multiple Chinese herbal formulas for reducing angry outbursts or rage due to a liver imbalance^[47] called liver yin deficiency or liver fire blazing.

In a lab study, angelica was effective at reducing VEGF^[48]. In another study, angelica was effective at increasing cognitive abilities and brain plasticity of rats when under chronic stress^[49]. Angelica also has demonstrated anti-endotoxin properties in multiple animal studies^[50]. This herb has demonstrated an inhibitory effect on Salmonella typhi, E. coli, Corynebacterium diptheriae, Vibrio cholerae, alpha-hemolytic streptococcus, and beta-hemolytic streptococcus^[51]. Another herb that is often used with angelica is peony.

White peony root, Chinese name Bai Shao, has anti-inflammatory, antibiotic, CNS calming, and digestion healing properties. In Chinese medicine, white peony is used to nourish the blood, treat anemia, regulate menstrual disorders, relieve pain, reduce night sweats, nourish, cool and soften the liver^[52]. A compound found in white peony called total glucosides was effective in reducing the abnormal proliferation of VEGF in a rat study^[53]. Paeoniflorin, another component of white peony, demonstrated liver protective^[54] and anti-endotoxin^[55] properties in multiple animal studies. Albiflorin, another compound in white peony, demonstrated similar anti-inflammatory properties compared to paeoniflorin^[56].

This herb has shown to have an inhibitory effect against Bacillus dysenteriae, E. Coli, Salmonella typhi, Pseudonomas aeruginosa, Staphyloccus aureus, beta-hemolytic streptococcus, and Diplococcus pneumoniae^[57]. Peony is often paired with angelica in herbal formulas for treating liver imbalances, including those that are marked by irritation, rage, and angry outbursts^[58]. Bupleurum is another herb used in traditional Chinese medicine for supporting the liver.

Bupleurum, Chinese name Chai Hu, has pathogen expelling, anti-malarial, liver harmonizing, and yang lifting properties. In Chinese medicine, bupleurum is used to treat infections with symptoms of fever, chills, fullness in the chest, bitter taste in the mouth, dry throat, poor appetite, nausea, vertigo, and irritability. This herb is often used to treat malaria, emotional distress, eye disorders, breast swelling and pain, irregular menstruation, jaundice, migraines, and prolapsed organs^[59]. In Chinese herbal formulas, this herb is used to release anger and frustration that is inexpressible^[60].

This herb has an inhibitory effect on B-hemolytic streptococcus, Vibrio cholerae, Mycobacterium tuberculosis, leptospirosis (a spirochete infection), influenza viruses, and hepatitus viruses Buplerum is cautioned in patients with excessive dryness and heat symptoms. There may an increased risk of acute pneumonitis when this herb is used with interferon^[61]. Polysaccharides found in this herb have anti-toxin properties^[62]. Bupleurum reduced depression in one human study by increasing Nerve Growth Factor (NGF) and Brain Derived Neurotrophic Factor (BDNF)^[63]. In a rat study, an herbal formula with bupleurum was effective at reducing inflammatory cytokines causing jaundice and liver hepatitis^[64]. Bupleurum is a component with angelica and white peony in a famous formula called “Rambling Powder” to treat liver stagnation^[65]. Withania somnifera is another herb for calming the emotions.

Withania somnifera, also called ashwagandha, has a very revered place in ayurvedic medicine. It’s properties are tonifying, replenishing, longevity enhancing, adaptogenic, stress reducing, anti-tumor, neuroregenerative, anti-arthritic, aphrodisiac, narcotic, diuretic, anthelmintic, astringent, thermogenic, and stimulant^[66].

Withania somnifera has been used to treat the following conditions: arthritis, inflammatory conditions, anxiety, insomnia, respiratory disorders, asthma, and bronchitis. It is also used to treat disorders of the nervous, immune, and the reproductive system. It is especially used to treat nervousness, depression, digestion problems, and low libido^[67]. This herb has also been used to treat gastric ulcers, uterine fibroids, dementia, memory problems, Parkinson’s, Huntington’s, Alzheimer’s disease, mitochondrial energy depletion, rheumatoid, and osteoarthritis^[68].

In one mouse study, Withania somnifera was effective at inhibiting obsessive compulsive behavior^[69]. In a rat study, Withania somnifera demonstrated liver protective and anti-inflammatory effects against gentamicin liver damage^[70]. This herb was also effective in multiple studies against Staphylococcus aureus, Methicilin Resistance Staphylococcus aureus (MRSA)^[71], Enterococcus spp.^[72], Escherichia coli, Salmonella typhi, Citrobacter freundii, Pseudomonas aeruginosa, Klebsiella pneumoniae^[73], Aeromonas hydrophila^[74], Plasmodium berghei^[75], Linoleic and oleic acids from Withania somnifera were effective at inhibiting streptococcus mutans biofilms^[76]. Withaferin A and withanone are compounds found in this herb that show inhibitiatory potential against leshmania protozoa^[77]. Withaferin A also inhibited the production of H. pylori induced inflammatory compound IL-1beta^[78], MMP-9^[79] produced by metastatic cancer cells, and VEGF produced by brain cancer cells^[80] in lab experiments. Using a combination of these herbs can help to fight the uncomfortable emotions triggered by a Bartonella infection.

People with Lyme disease that have uncontrolled anger, rage and obsessive behaviors may have a stealthy Bartonella infection affecting their liver and nervous system. Similar to canceling a credit card with fraudulent charges, these herbs may help to stop the spread of Bartonella through inhibiting VEGF. By harmonizing and decongesting the liver, these herbs may help to reduce angry outbursts and obsessive compulsive behaviors. Using liposomal anti-Bartonella herbs may be more effective in stopping Bartonella inside the liver, the basal ganglia in the brain, and in endothelial cells. Since some of these herbs have cautions on their use, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

In deer ticks and lone star ticks, nematodes have been detected
In multiple tick studies, nematodes have been detected in lone star ticks found in Maryland^[2] and Virginia^[3], and in deer ticks from Connecticut^[4]. Ticks are capable of transmitting nematodes when they feed on a host^[5]. Other vectors that can transmit nematodes are mosquitoes and black flies^[6]. Once they infect a host, adult nematodes mate and then release thousands of very small larva called “microfilariae” into the blood. Microfilariae circulate throughout the host and can end up in the nervous system^[7]. These microfilariae evolve into larvae which can eat through the brain and can cause a wide range of symptoms.

Nematodes produce many symptoms when they infect the brain and spinal fluid
Larval nematodes in the nervous system can damage tissues and produce masses called granulomas. They can also cause fibrosis, blockages in cerebral blood vessels, or inflammation resulting in meningitis, encephalitis or localized inflammation^[8], weakness, blurred vision, stomach flu^[9], and even death. In a Taiwan study, patients infected with nematodes reported meningitis, brain inflammation, fever, vomiting, headache, and neuropathy. Two patients died from their infection. In some patients, nematodes were recovered from their cerebral-spinal fluid (CSF). Elevated levels of inflammatory markers vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), and matrix metalloproteinase 9 (MMP-9) were also detected in patient’s CSF fluid^[10]. Research shows that nematodes can also manipulate the immune system response.

Nematodes produce compounds to deflect how the immune system attacks parasites
One research study on a nematode called B. Malayi, identified proteins that it releases to manipulate the immune response in favor of a parasitic infection^[11]. Another study on a filarial nematode infection illustrated how these parasites inhibit the inflammatory response by the immune system^[12]. In most cases, anti-parasitic medications are used to treat nematode infections in the nervous system.

Anti-parasitic medications help to kill nematode infections in the brain and spinal fluid
Anti-parasitic medications called antihelminthics are used to treat nematodes in the nervous system including: Mebendazole, Pyrantel pamoate, Thiabendazole, Diethylcarbamazine (DEC), Ivermectin^[13], Moxidectin^[14], and Alinia^[15]. Ivermectin and moxidectin are the most widely administrated antihelminthic medications for nematode infections and unfortunately, their widespread and frequent use has led to high level of resistance to these drugs^[16]. Ivermectin only kills the microfilariae, not the adult nematode^[17]. DEC can worsen onchocercal nematode eye infections. In patients with a nematode infection called loiasis, DEC can cause serious adverse reactions, including encephalopathy and death, depending upon the density of the parasites. DEC is only available in the US from the CDC upon submitting positive lab results^[18]. A mechanism within nematodes called a “drug effux pump” is believed to enable these parasites to develop drug resistance^[19]. Killing nematodes can lead to significant Herxheimer reactions.

A symbiotic bacteria within nematodes is the source of Herxheimer toxins
Wolbachia is a symbiotic bacteria which enables normal development and fertility of nematodes^[20]. Wolbachia belong to the order Rickettsiales and is closely related to Anaplasma, Ehrlichia and Rickettsia^[21]. Fortunately, this bacteria does not infect people. When nematodes are killed off by anti-parasitic drugs, Wolbachia cannot survive without their host and are killed, which releases their endotoxins. Wolbachia toxins stimulate the production of pro-inflammatory compounds including tumor necrosis factor alpha (TNF)-alpha, Interleukin-1 (IL-1), and Interleukin-12 (IL-12)^[22]. In an animal study, Wolbachia surface protein upregulated (IL)-1beta, IL-6, and tumor necrosis factor^[23]. These endotoxins and inflammatory compounds can produce painful symptoms associated with a Herxheimer reaction. A combination of anti-parasitic and antibiotic medications is more effective at reducing adult and microfilariae forms of nematodes.

A combination of medications which kill both the adult and microfilariae forms is more effective
Recent drug strategies combine Ivermectin for microfilariae and doxycycline to kill Wolbachia which eventually kills the adult nematodes in the nervous system. This combination drug treatment is recommended for six weeks^[24]. Another animal study combined DEC with liposomal doxycycline and liposomal rifampin resulting in significant increase in microfilariae die off and a marginal increase in the die off of adult nematodes^[25]. Other studies demonstrate the inhibitory effect of anti-Rickettsia antibiotics like tetracycline, rifampin, and azithromyacin on adult nematodes^[26].

What else can help people to expel brain-eating nematodes from their central nervous system who have persistent neurological Lyme disease, multiple sclerosis, dementia, brain tumors, or Alzheimer’s disease?

Here are four strategies for expelling brain-eating nematodes from the central nervous system
A combination of remedies for attacking both the adult and microfilariae forms is the most effective at reducing the overall numbers of parasites. Formulating remedies into microparticles called liposomes enhances the efficacy of anti-parasitic herbs and essential oils for killing the different life stages of nematodes^[27] and possibly their symbiotic bacteria.

Clearing Brain-Eating Nematodes Strategy #1: Essential Oils
Essential oils have been found to inhibit different species of nematodes.

Thyme essential oil was effective at inhibiting Meloydogine javanica^[28] and larvae from the Anisakis nematode^[29]. Thyme essential oil was also effective against gram negative bacteria: Pseudomonas aeruginosa^[30], Salmonella spp.^[31], and E. Coli^[32]. Thyme combined with oregano oil reduced mRNA levels of pro-inflammatory cytokines IL-1beta, IL-6, GM-CSF, and TNFalpha^[33].

Palmarosa essential oil was effective against Caenorhabditis elegans^[34] and Haemonchus contortus^[35] in separate studies. This oil was also effective at inhibiting E. Coli^[36] and Aspergillus fumigatus^[37]. Palmarosa oil also reduced pro-inflammatory compounds TNF-α, IL-1β, and IL-8^[38] and increased anti-inflammatory IL-10 in lab studies^[39].

Clove bud essential oil was highly effective at reducing^[40] Meloidogyne incognita egg hatch 50% and killing second stage juveniles (J2) as much as 100% in a lab study^[41]. Eugenol, the primary compound in clove bud oil, in one rat study reduced expression of VEGF, MMP-2, and MMP-9^[42], which are elevated in nematode infections. Processing these oils into a liposomal micronized form increases their penetration into the nervous system^[43]. Adding nanoparticles of silver to liposomal oils may further enhance their anti-microbial properties.

Clearing Brain-Eating Nematodes Strategy #2: Nanoparticle Silver
In multiple lab studies, nanoparticles of silver were effective at reducing motility and killing microfilariae of Brugia malayi^[44], demonstrated antifilarial activity against microfilaria of S. Cervi^[45], disrupted metabolism of Caenorhabditis elegans^[46], and killed most of Meloidogyne incognita^[47]. Encapsulating nanoparticles of silver along with essential oils into a liposomal remedy may increase their anti-parasitic and anti-symbiotic bacterial properties. When nanoparticle silver is combined with tea tree essential oil into a liposome, their antimicrobial efficiency is enhanced against Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans^[48]. Silver nanoparticles may reduce inflammation from nematodes by inhibiting IL-1beta and VEGF induced permeability as reported in a pig study^[49] and reducing MMP-2 and MMP-9 in another rat study^[50]. Herbs have also been effective for treating nematode infections for thousands of years.

Clearing Brain-Eating Nematodes Strategy #3: Herbs
In addition to essential oils and silver, herbs have been used for centuries for fighting nematode infections.

Andrographis, Chinese name Chuan Xin Lian, has been effective at inhibiting Haemonchus contortus^[51], microfilaricidal activity against Dirofilaria immitis filarids^[52], antifilarial activity against adult worms of subperiodic Brugia malayi^[53], killing in vitro the microfilaria of Dipetalonema reconditum in dogs^[54], and anthelmintic activity against Ascaris lumbricoides^[55]. This herb is also used in Chinese medicine against leptospirosis, another spirochete infection^[56]. Andrographis was also effective at reducing inflammatory compounds IL-1α, IL-1β, and IL-6 in a lab study^[57]. A compound in Andrographis called andrographolide inhibits expression of inflammatory compounds MMP-2, IL-1beta^[58] and VEGF^[59] in lab studies.

Ajowan, ajwain, or Trachyspermum ammi has been effective against multiple species of nematodes in multiple studies. Methanolic extract of fruits of Trachyspermum ammi were effective against adult bovine filarial Setaria digitata worms and demonstrated macrofilaricidal activity and female worm sterility in vivo against B. Malayi^[60].

Lantana camara is an ornamental shrub which is very hardy and is used medicinally through much of the world. This herb contains triterpenoids pomolic acid, lantanolic acid, lantoic acid, camarin, lantacin, camarinin, and ursolic acid which exhibited 100% mortality in 24 – 48 hours against the nematode Meloidogyne incognita^[61]. In other studies, a lantana extract killed adult Brugia malayi nematodes and sterilized many of the surviving female worms, and demonstrated strong microfilaricidal and sterilization efficacy with mild macrofilaricidal action against Acanthocheilonema viteae^[62]. Not only herbs, but also tiny electrical frequencies can help to stop nematodes that have infected the brain and spinal fluid.

Clearing Brain-Eating Nematodes Strategy #4: Frequency Specific Microcurrent
Frequency Specific Microcurrent uses millionth of an amp electrical currents to reduce parasitic and bacterial infections, toxins and inflammation^[63]. Frequencies for inhibiting parasitic worms, symbiotic bacteria, neutralizing toxins and inflammation, reducing tumors, and promoting healing are paired with frequencies to target infected areas of the nervous system: the brain, forebrain, meninges, basal ganglia, spinal cord, spinal fluid, cranial nerves, and eyes^[64]. These paired frequencies have also been helpful in reducing symptoms in patients diagnosed with multiple sclerosis, autism, brain inflammation, mold toxicity, and neurological Lyme disease. These four strategies may help people with neurological Lyme to stop an underlying parasitic nematode brain infection.

A combination of anti-parasitic remedies and treatments can help to overcome a chronic neurological Lyme and nematode infection
People diagnosed with multiple sclerosis, Alzheimer’s disease, dementia, or brain tumors may have hidden parasitic nematodes along with Lyme disease in their nervous system. Just like finding and eliminating the wasp nest, expelling parasitic nematodes that harbor Lyme bacteria may help to improve neurological symptoms and memory recall. Using liposomal anti-parasitic and anti-symbiotic bacteria remedies and treatments may be effective in eliminating larger parasites and the Lyme bacteria they contain.

Anti-toxin treatments and remedies may also help with reducing inflammatory compounds which may lower toxic Herxheimer pain and discomfort. Making these remedies into micronized liposomes enhances their delivery into the nervous system and may increase their anti-nematode effectiveness. Since some of these treatments and remedies require specialized training, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

I used to play football and baseball with other neighborhood boys at Mr. Johnson’s field. Occasionally we’d have to go looking for one of our balls at the far end of the field which had tall grass and weeds. Sometimes I’d come out with “hitchhiker” weed seeds clinging to my clothes.

How are hitchhiker seeds similar to people with Lyme disease that have chronic digestion problems?

Just like seeds that sneak on to your clothes, Listeria can be a dangerous pathogen which sneaks into the intestines
In several different recalls of food products, Listeria monocytogenes was cited as a contaminant in multiple food processing plants which produce frozen food, fruit, ice cream, cheese, and sunflower seeds. In another incidence, Listeria was found in whole cantaloupes that ended up sickening 147 people and resulted in 43 fatalities^[1]. According to one CDC report, Listeria can be fatal in 21% of cases^[2] even despite early antibiotic treatment^[3]. Fatality may be as high as 40-60% in patients with a central nervous system infection and concurrent debilitating disease^[4]. People over 65, pregnant women and especially their unborn children, and immune compromised patients like people with chronic Lyme or co-infections are at greater risk. Fortunately, the risk of getting a Listeria infection is low, about 2-3 people per million in the US. However, the risk is greater in immune compromised people, even at low doses of Listeria contamination on food^[5]. This infection usually starts with symptoms in the digestion system.

Listeria often presents with bloating, nausea, and diarrhea
This infection can produce symptoms of fever and muscle aches, sometimes preceded by diarrhea or other gastrointestinal symptoms. In 55-70% of cases, Listeria can affect the central nervous system (CNS)^[6].  When Listeria spreads beyond the digestion tract, it can produce symptoms of headache, stiff neck, confusion, loss of balance, convulsions, meningitis, septicemia, and death^[7]. Some immune compromised patients may not have any symptoms. Listeria employs multiple methods to spread through unsuspecting people.

Listeria uses multiple methods to help it to spread through the body
The first line of defense against food borne Listeria are the endothelial cells which line the intestines. Listeria employs multiple strategies to invade several different types of cells and spread through the body: intestinal epithelial cells, hepatocytes, placental cytotrophoblasts, endothelial cells, macrophages and other immune cells^[8]. In one lab study, listeriolysin O (LLO) is a toxin produced by Listeria which enables it to move freely inside of and to propagate between endothelial cells^[9]. This toxin also disables “T” cells which enable this bacteria to evade the immune system and survive longer^[10]. Listeria has also developed drug resistance to multiple antibiotics.

Listeria can persist due to drug resistance to many antibiotics
Unfortunately, mutant strains of Listeria have developed resistance to several antibiotics including: ampicillin, cephalothin, penicillin, meticillin, oxacillin^[11],  tetracycline, streptomycin, cefotaxime, and gentamicin^[12]. Listeria uses a mechanism called an effux pump to sample drug molecules to develop drug-resistance^[13]. This bacteria can also produce biofilms under which many species of pathogens may live, which suggests that Listeria is likely capable of long-term infection in the gut^[14]. In one study on sanitizers, Listeria under a biofilm demonstrated increased resistance of 1000 times^[15]. In another lab study, Listeria has also been shown to be capable of receiving drug resistant genes from other bacteria that contaminate food^[16]. Unfortunately, some Lyme disease patients with chronic digestion problems have tested positive for resonant frequencies for Listeria in their intestines.

What else can help people with Lyme disease to fight a drug-resistant, biofilm forming, intracellular Listeria gut and central nervous system infection?

Here are five strategies for stopping Listeria infections in the gut and the central nervous system
Here are four strategies for helping to stop Listeria from spreading. Making remedies into a small particle size can increase their anti-Listeria properties. When anti-Listeria medicines were processed into small particles and wrapped with a lipid or a fat outer layer called a liposome, they had a 90-fold greater effect at killing the intracellular infection in mice^[17]. Liposomal remedies have been shown to be more effective at penetrating and delivering remedies into Listeria infected cells than their non-liposomal equivalents^[18]. In other studies, herbs, specific frequencies of light, and dietary changes inhibited Listeria.

Listeria Stopping Strategy #1: Essential Oils
In one lab study, five plant essential oils: bay, clove, cinnamon, nutmeg and thyme significantly reduced the toxin listeriolysin O^[19], which can help to prevent Listeria monocytogenes from spreading through the body. In another lab study, nanoemulsions of anise oil were more effective at inhibiting Listeria than anise essential oil^[20]. Other lab studies indicated the effectiveness of oregano^[21], lemongrass^[22], spearmint^[23], clove^[24], myrtle^[25], ajowan^[26], orange^[27], peppermint^[28], geranium^[29], artemisia annua^[30], cinnamon Chinese cassia, red thyme^[31], lemon and cinnamon^[32] essential oils against Listeria monocytogenes. In lab experiments, thyme and oregano^[33] essential oils were also effective at eliminating the biofilm forms of Listeria. Encapsulation the oils in liposomes, increases their effectiveness at targeting intracellular L. monocytogenes in endothelial cells^[34] and the central nervous system^[35]. Not only oils can help with stopping Listeria, so can specific wavelengths of light.

Listeria Stopping Strategy #2: Light Therapy
Light Emitting Diode (LED) frequencies of 405 nm^[36] and 461 nm^[37] inactivated L. monocytogenes in multiple lab experiments. Applying these wavelengths to the skin may help with stopping a cutaneous Listeria^[38] infection. In studies on the penetration depth of laser wavelengths of 405 nm, this frequency was able to penetrate to a depth of 0.08 mm with 55% transmission into fair colored skin, and 2.5% in darker skin^[39]. In addition to light, herbs can also help with stopping Listeria.

Listeria Stopping Strategy #3: Herbs
In addition to essential oils and light frequencies, these herb extracts have anti-Listeria properties in one study: rosemary, Echinacea angustifolia, thyme, tea tree, and peppermint^[40]. In other studies, green tea was effective at inhibiting Listeria in food^[41]. A green tea compound called epigallocatechin gallate (ECGC) was also effective at inhibiting the intracellular growth of L. Monocytogenes in a macrophage study^[42]. Processing these herbs into small particle liposomes enhances their ability to penetrate and stop intracellular Listeria^[43] and potentially disrupt it’s biofilms^[44]. Not only herbs, but also tiny electrical frequencies can help to stop a Listeria infection.

Listeria Stopping Strategy #4: Frequency Specific Microcurrent
Frequency Specific Microcurrent uses millionth of an amp electrical currents to reduce bacterial infections, toxins and inflammation^[45]. Frequencies for reducing pathogens, neutralizing toxins and inflammation, and promoting healing are combined with frequencies to target Listeria hiding inside blood cells^[46], and organs like the intestines^[47], liver, spleen^[48], and the central nervous system^[49]. These paired frequencies have been helpful in reducing symptoms in patients with meningitis, headaches, and confusion. In addition to microcurrent, dietary changes can also help to fight Listeria.

Listeria Stopping Strategy #5: Dietary Changes
In multiple studies, these foods and supplements inhibited the growth of Listeria: virgin olive oil^[50], zinc and isomeric vitamin A^[51], feijoa fruit extract from New Zealand^[52], Lactobacilus^[53] and Bifidobacterium^[54] probiotics. Eliminating alcohol intake may also help with boosting the strength of your innate immunity against Listeria^[55]. Multiple strategies can help people with Lyme to stop a persistent Listeria gut or brain infection.

A combination of anti-Listeria strategies can help to resolve a chronic gastrointestinal problems or infections in people with Lyme disease
Similar to taking the hitchhiking seeds off your clothes, anti-Listeria remedies and treatments may help to resolve chronic digestion problem, gut infections and meningitis. Processing these oils and herbs into a small particle liposome can enhance their antimicrobial, antibiofilm properties, and ability to penetrate inside cells and into the central nervous system. Some patients will also take these oils or herb extracts in an enema to increase their delivery into the intestines. Since some of these oils and herbs have cautions on their use, work with a Lyme literate natural remedy practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-practitioner relationship, and should not be used as a substitute for professional diagnosis and treatment.

Please consult your health care provider, or contact the Two Frogs Healing Center for an appointment, before making any healthcare decisions or for guidance about a specific medical condition. The Two Frogs Healing Center expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. The Two Frogs Healing Center does not endorse specifically any test, treatment, or procedure mentioned on the site.

By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by the Two Frogs Healing Center. If you do not agree to the foregoing terms and conditions, you should not enter this site.

DISCLAIMER:-

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-practitioner relationship, and should not be used as a substitute for professional diagnosis and treatment.

Please consult your health care provider, or contact the Two Frogs Healing Center for an appointment, before making any healthcare decisions or for guidance about a specific medical condition. The Two Frogs Healing Center expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. The Two Frogs Healing Center does not endorse specifically any test, treatment, or procedure mentioned on the site.

By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by the Two Frogs Healing Center. If you do not agree to the foregoing terms and conditions, you should not enter this site.

ONLINE Live Six Week Training: Essential Oils for Healing Persistent Lyme Symptoms for Medical Providers

Learn to Reduce Persistent Symptoms Faster in Your Lyme Disease Patients Through Essential Oils

– Do you have Lyme patients that continue to report recurring pain, fatigue and mental fog?

– Are you frustrated by the lack of patient improvement with
Lyme protocols?

– Learn about safe amounts of essential oils for internal use
to treat stubborn Lyme symptoms.

Sign up by April 28th and receive a BONUS cold laser and an essential oil remedy laser kit for Lyme and other infection symptoms worth $100.

Participants will get six one-hour live training sessions every Friday 3pm – 4pm EST from April 29th – June 3rd. All sessions are recorded and available for replay 24/7. Participants will also get bonus videos on using cold laser essential oils and making liposomal essential oil remedies for resolving persistent Lyme symptoms.

You can see two videos, one on specific essential oils for Lyme and co-infections and a second of an indepth case study on how oils helped heal neurological Lyme disease and co-infections here:

JASA / Acupuncture Today Free Report on Essential Oils and Herbs for Lyme Disease

Registration closes Thursday April 28th. Space is limited…
This training costs $900, which is 25% off the cost of the live event.

Questions about the training?
Please email me at TwoFrogsHealingCenter at gmail.com

– Greg

For people with Lyme disease and co-infections who crave sweets and carbohydrates
by Greg Lee

– Greg

Next step: Come to our evening lecture Getting Rid of Lyme Disease in Frederick, Maryland on Monday April 4th at 6pm to learn more about sweeteners, herbs, and essential oils for protecting yourself from Lyme disease and co-infections.

https://goodbyelyme.com/events/get_rid_lyme

Also learn about effective remedies and treatments for relieving persistent symptoms of Lyme and co-infections including: cold laser, Frequency Specific Microcurrent, cupping, LED therapy, moxabustion, acupuncture, liposomal herbs, essential oils, bee venom, and more!

P.S. Do you have experiences where sweeteners helped you to fight and heal Lyme disease and co-infections? Tell us about it.