Five Essential Oils for Stopping Relapsing Symptoms Caused by Lyme Disease That Thrives Despite Multiple Antibiotics

For people with recurring Lyme disease symptoms that still struggle despite months of several antibiotics

by Greg Lee

Have you heard of the Greek mythical monster called the Hydra? It was a huge serpent with nine poisonous heads. Heracles the Greek divine hero, aka Hercules in Roman mythology, was sent to kill this monster. Whenever Heracles cut off one head, two grew back in it’s place. Heracles was soon overwhelmed by the growing number of serpent heads. Fortunately, his nephew Iolaus used a torch to cauterize the severed stumps before more heads could grow back. No longer swarmed by double serpent heads, Heracles overcame and killed the hydra.

How is a hydra that can keep growing new heads similar to fighting Lyme disease that persists despite antibiotic treatment?

Similar to the mythical hydra, persistent Lyme disease can keep spreading despite blasting it with powerful antibiotics
In lab studies, Lyme disease bacteria can develop persistent forms called round bodies and cysts that are not killed by antibiotics. Lyme bacteria can also produce a slime called “biofilm” which can make infections up to 1000x more drug resistant[1]. Lyme patients with persistent infections can continue to struggle with multiple recurring symptoms.

Lyme disease patients can have recurring, multiple symptoms despite antibiotic treatment
Despite receiving antibiotic therapy, patients diagnosed with Lyme disease have reported recurring symptoms of fatigue, muscular and joint pain, neurological impairment[2], arthritis[3], upper and lower extremity neuropathic pain[4], and dementia[5]. Approximately 10-20% of Lyme patients report recurring symptoms after two to four weeks of antibiotics[6]. One theory for this relapse is that persistent forms of Lyme disease that have survived antibiotic treatment. These bacteria are not stopped by antibiotics and continue to create recurring symptoms. One area where these persistent forms can create problems is in the brain.

Brain samples from Alzheimer’s patients contain persistent forms of Lyme disease
Atypical and cystic forms of Lyme disease in were found in the cerebral cortex region of the brain of patients diagnosed with neurological Lyme[7]. Lyme disease biofilms were also discovered in the the brain tissues of patients diagnosed with Alzheimer’s[8]. Given the increased drug resistant nature of biofilms and persistent forms of Lyme disease, some Lyme literate medical providers have resorted to using multiple  antibiotics.

Multiple antibiotics are being used to target persistent forms of Lyme disease
In a lab study, Lyme disease persisters were killed more effectively with a combination of three antibiotics: Daptomycin, cefuroxime, and doxycycline[9]. A Lyme literate doctor recommended the use of multiple antibiotics including one called Dapsone for minimum length of seven months or longer[10]. Unfortunately, there can be multiple side effects from prolonged antibiotic treatment for Lyme disease.

Patients can experience multiple side effects from prolonged antibiotic treatment for Lyme
Lyme disease patients receiving oral and intravenous antibiotics have reported different side effects from skin photosensitivity reactions and gastrointestinal symptoms[11], decreased white blood cells, fever, hepatitis, Clostridium difficile-associated diarrhea[12], meningitis[13], and IV port infections[14]. Lyme patients also report increased digestion issues including leaky gut syndrome, irritable bowel syndrome, or toxic die-off aka “Herxheimer” reactions[15] as a result of their antibiotic therapy. In a rare case, prolonged antibiotic treatment has been associated with anemia and kidney damage[16].

Are there natural remedies that can help to reduce recurring symptoms by targeting antibiotic persistent forms of Lyme disease?

Fortunately, there are five essential oils that have been effective against persister forms of Lyme disease
In a recent study, five essential oils: oregano, clove bud, cinnamon bark, citronella, and geranium were more effective at eliminating persister forms of Lyme disease than the antibiotic daptomycin[17]. Many of these essential oils have been used safely for years in our food supply[18] and to help patients with Lyme disease to reduce relapsing symptoms[19]. These oils have multiple healing and infection fighting properties in lab and animal studies. Microparticle “liposome” essential oils have demonstrated greater antimicrobial properties in lab studies[20].

Anti-Lyme Persister Essential Oil #1: Oregano
Oregano essential oil eradicated all Lyme disease persister cells and dissolved biofilms in a lab study[21]. The major antimicrobial components of this oil are carvacrol and thymol[22]. In multiple studies, oregano oil has also been effective against multi-drug resistant E. Coli and it’s biofilms[23], Salmonella species, Staphylococcus aureus, Bacillus subtilis, multi-drug resistant Pseudonomas aeruginosa, Candida species, and Aspergillus niger[24]. This oil has the ability to disrupt the “quorum sensing” communication signals that pathogens use to make biofilms in food preservation studies[25], and can inhibit biofilm formation in multiple pathogens[26].

In a pig study, oregano oil increased intestinal barrier integrity, decreased endotoxins, and lower inflammatory compounds[27]. In a mouse study, a combination of oregano and thyme essential oil reduced the levels of pro-inflammatory cytokines IL-1beta, IL-6, GM-CSF, and TNFalpha and reduce damage to the colon[28].

This essential oil is contraindicated in pregnancy and breast feeding. This oil has anti-coagulant properties and is cautioned with the use of diabetic medications, anticoagulant medications, after major surgery, peptic ulcer, hemophilia, and other bleeding disorders. It is also cautioned against using this oil on diseased or damaged, or hypersensitive skin, and with children under 2 years old[29]. In addition to oregano oil, clove bud oil has excellent anti-Lyme properties.

Anti-Lyme Persister Essential Oil #2: Clove Bud
Clove bud essential oil also eradicated all Lyme disease persister cells and biofilms in a lab study[30]. Eugenol is the main antimicrobial ingredient in this oil. In multiple lab studies, clove oil inhibits Salmonella typhimurium, E. coli, B. cereus, Listeria innocua, Morganella morganii, Listeria monocytogenes, Enterobacteriaceae, S. aureus, and Pseudomonas species[31]. This oil also posses potent antifungal properties against Candida albicans[32] and Aspergillus flavus[33]. In lab studies, clove bud oil attenuates E. coli biofilm production[34].

In another lab study, this oil also inhibits the production of inflammatory compounds IL-1beta and IL-6[35] which are often elevated in patients with Lyme disease[36].

Clove bud oil use is cautioned in pregnancy. This oil has anti-coagulant properties and is cautioned with the use of diabetic medications, anticoagulant medications, after major surgery, peptic ulcer, hemophilia, and other bleeding disorders. It may interact with pethidine, MAOIs or SSRIs. It is also cautioned against using this oil on diseased or damaged, or hypersensitive skin, and with children under 2 years old This oil has US Food and Drug Administration (FDA) generally recognized as safe (GRAS) status[37]. Similar to clove bud oil, cinnamon bark has excellent anti-Lyme properties.

Anti-Lyme Persister Essential Oil #3: Cinnamon Bark
In a lab study, cinnamon bark essential oil eradicated all Lyme disease persister cells and biofilms[38]. The main active compounds in cinnamon bark oil are cinnamaldehyde and eugenol[39]. Cinnamon bark oil also inhibits methicillin resistant Staphylococcus aureus (MRSA) and it’s biofilms, Aspergillus ochraceus, Fusarium moniliforme[40], Brucella abortus[41], multidrug resistant Pseudonomas aeruginosa[42], and Candida albicans and it’s biofilms[43].

In a human skin lab study, cinnamon bark oil reduced inflammatory compounds matrix metalloproteinase-1 (MMP-1), and plasminogen activator inhibitor-1 (PAI-1)[44]. PAI-1 is often elevated and slows the recovery in Lyme patients by creating a condition called hypercoagulation or thick blood[45]. When encapsulated into a microparticle liposome, cinnamon bark oil was more stable and was effective longer against MRSA and it’s biofilms[46].

Cinnamon bark oil is contraindicated in pregnancy and breast feeding. This oil has anti-coagulant properties and is cautioned with the use of diabetic medications, anticoagulant medications, after major surgery, peptic ulcer, hemophilia, and other bleeding disorders. It has a high risk of skin sensitization, is also strongly cautioned against using this oil on diseased or damaged, or hypersensitive skin. This oil has FDA GRAS status[47]. Similar to cinnamon, citronella has anti-Lyme properties.

Anti-Lyme Persister Essential Oil #4: Citronella
In a lab study, citronella essential oil was partially effective against Lyme disease persister cells in a 21-day experiment[48]. The main active component in citronella oil is citronellal[49]. In lab experiments, citronella oil demonstrates excellent antifungal properties against Aspergillus niger, Aspergillus flavus Penicillium species[50], Candida albicans and it’s biofilms[51]. In a diabetes wound study on mice, citronella oil inhibited Candida glabrata and Candida tropicalis and decreased expression of tumor necrosis factor alpha (TNF-α) and Interleukin 1β (IL-1β)[52].

Caution: citronella oil may interact with drugs metabolized by CYP2B6, which include alfentanil, methadone, and propofol. This oil has FDA GRAS status[53]. Just like citronella, geranium reduced persistent forms of Lyme disease.

Anti-Lyme Persister Essential Oil #5: Geranium Bourbon
In a lab study, geranium essential oil was partially effective against Lyme disease persister cells in a 21-day experiment[54]. The main active ingredients in this oil are citronellol and geraniol[55]. In a lab study, geranium bourbon oil was effective at inhibiting Staphylococcus aureus[56], multi-drug resistant S. Aureus and MRSA[57]. Geranium oil had an antibiotic effect against Bacillus cereus, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus in another lab study[58].

This oil was also effective at reducing inflammatory compounds Interleukin-6 (IL-6), Interleukin-1, (IL-1), Interleukin-2 (IL-2) and Cyclooxygenase-2 (COX-2) levels and increased anti-inflammatory Interleukin-10 (IL-10) caused by Candida albicans in a lab study[59]. This oil is cautioned with the use of diabetes medications, and drugs metabolized by CYP2B6, which include alfentanil, methadone, and propofol. This oil has FDA GRAS status[60]. These essential oils in combination may help to reduce relapsing symptoms caused by persistent forms of Lyme disease.

Essential oils may help to reduce recurring symptoms caused by antibiotic persister forms of Lyme disease
Similar to cauterizing the severed heads of the mythic Hydra monster so they don’t grow back, a powerful combination of essential oils may help you to overcome persister forms of Lyme disease that are not killed by antibiotics. Formulating these remedies into microparticle liposomes may enhance the stability and extend their antimicrobial activity of these essential oils. Since these essential oils have cautions and contraindications on their use, work with a Lyme literate essential oil practitioner to develop a proper, safe, and effective essential oil formulation for your condition.

– Greg

P.S. Do you have experiences where treatment or remedies helped you reduce recurring symptoms from persistent Lyme disease? Tell us about it.

>> Next step: Come to our live evening lecture: Getting Rid of Lyme Disease in Frederick, Maryland on Monday November 6th at 6pm to learn more about treatments and remedies for multiple infections, natural methods for reducing neurological problems, inflammation, and pain caused by Lyme disease, co-infections, parasites, and mold. https://goodbyelyme.com/events/get_rid_lyme


1 Potera, Carol. “ANTIBIOTIC RESISTANCE: Biofilm Dispersing Agent Rejuvenates
Older Antibiotics.” Environmental Health Perspectives 118, no. 7 (July 2010): A288.
2 Feng, Jie, Shuo Zhang, Wanliang Shi, and Ying Zhang. “Ceftriaxone Pulse Dosing
Fails to Eradicate Biofilm-Like Microcolony B. Burgdorferi Persisters Which Are Sterilized
by Daptomycin/ Doxycycline/Cefuroxime without Pulse Dosing.” Frontiers in
Microbiology 7 (2016): 1744. https://doi.org/10.3389/fmicb.2016.01744.
3 Ghosh, Srimoyee, and Brigitte T. Huber. “Clonal Diversification in OspA-Specific
Antibodies from Peripheral Circulation of a Chronic Lyme Arthritis Patient.” Journal of
Immunological Methods 321, no. 1–2 (April 10, 2007): 121–34.
https://doi.org/10.1016/j.jim.2007.01.007.
4 Mearini, Massimo, Stefano Podetta, Emanuela Catenacci, Patrizia d’Auria, Claudio
Cornali, and Pietro Mortini. “Spinal Cord Stimulation for the Treatment of Upper and
Lower Extremity Neuropathic Pain due to Lyme Disease.” Neuromodulation: Journal of
the International Neuromodulation Society 10, no. 2 (April 2007): 142–47.
https://doi.org/10.1111/j.1525-1403.2007.00102.x.
5 Blanc, Frederic, Nathalie Philippi, Benjamin Cretin, Catherine Kleitz, Laetitia Berly,
Barbara Jung, Stephane Kremer, et al. “Lyme Neuroborreliosis and Dementia.” Journal
of Alzheimer’s Disease: JAD 41, no. 4 (2014): 1087–93. https://doi.org/10.3233/JAD-
130446.
6 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017): 169.
https://doi.org/10.3389/fmed.2017.00169.
7 Miklossy, Judith, Sandor Kasas, Anne D. Zurn, Sherman McCall, Sheng Yu, and
Patrick L. McGeer. “Persisting Atypical and Cystic Forms of Borrelia Burgdorferiand
Local Inflammation in Lyme Neuroborreliosis.” Journal of Neuroinflammation 5
(September 25, 2008): 40. https://doi.org/10.1186/1742-2094-5-40.
8 MacDonald, A. Borrelia Biofilms Dwell Inside of Amyloid Alzheimer’s Plaques: 100
consecutive Plaques Examined By Alan B. MacDonald, MD. College of American
Pathologists Presntation September 11, 2015
9 Feng, Jie, Shuo Zhang, Wanliang Shi, and Ying Zhang. “Activity of Sulfa Drugs and
Their Combinations against Stationary Phase B. Burgdorferi In Vitro.” Antibiotics (Basel,
Switzerland) 6, no. 1 (March 22, 2017). https://doi.org/10.3390/antibiotics6010010.
10 Horowitz, R. Discussion with Panel of Experts. ILADS 2016, Philadelphia, PA.
November 6, 2016.
11 Ogrinc, Katarina, Mateja Logar, Stanka Lotric-Furlan, Dasa Cerar, Eva Ruzić-Sabljić,
and Franc Strle. “Doxycycline versus Ceftriaxone for the Treatment of Patients with
Chronic Lyme Borreliosis.” Wiener Klinische Wochenschrift 118, no. 21–22 (November
2006): 696–701. https://doi.org/10.1007/s00508-006-0698-7.
12 Nadelman, R. B., Z. Arlin, and G. P. Wormser. “Life-Threatening Complications of
Empiric Ceftriaxone Therapy for ‘Seronegative Lyme Disease.’” Southern Medical
Journal 84, no. 10 (October 1991): 1263–65.
13 Cimperman, J., V. Maraspin, S. Lotric-Furlan, E. Ruzić-Sabljić, and F. Strle. “Lyme
Meningitis: A One-Year Follow up Controlled Study.” Wiener Klinische Wochenschrift
111, no. 22–23 (December 10, 1999): 961–63.
14 Stricker, R. B., C. L. Green, V. R. Savely, S. N. Chamallas, and L. Johnson. “Safety
of Intravenous Antibiotic Therapy in Patients Referred for Treatment of Neurologic Lyme
Disease.” Minerva Medica 101, no. 1 (February 2010): 1–7.
15 Kadam, Pooja, Neal A. Gregory, Bernhard Zelger, and J. Andrew Carlson. “Delayed
Onset of the Jarisch-Herxheimer Reaction in Doxycycline-Treated Disease: A Case
Report and Review of Its Histopathology and Implications for Pathogenesis.” The
American Journal of Dermatopathology 37, no. 6 (June 2015): e68-74.
https://doi.org/10.1097/DAD.0000000000000093.
16 De Wilde, Maarten, Marijn Speeckaert, Rutger Callens, and Wim Van Biesen.
“Ceftriaxone-Induced Immune Hemolytic Anemia as a Life-Threatening Complication of
Antibiotic Treatment of ‘Chronic Lyme Disease.’” Acta Clinica Belgica 72, no. 2 (April
2017): 133–37. https://doi.org/10.1080/17843286.2016.1180829.
17 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
18 Hyldgaard, Morten, Tina Mygind, and Rikke Louise Meyer. “Essential Oils in Food
Preservation: Mode of Action, Synergies, and Interactions with Food Matrix
Components.” Frontiers in Microbiology 3 (January 25, 2012).
https://doi.org/10.3389/fmicb.2012.00012.
19 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017): 169.
https://doi.org/10.3389/fmed.2017.00169.
20 Low, W. L., C. Martin, D. J. Hill, and M. A. Kenward. “Antimicrobial Efficacy of
Liposome-Encapsulated Silver Ions and Tea Tree Oil against Pseudomonas Aeruginosa,
Staphylococcus Aureus and Candida Albicans.” Letters in Applied Microbiology 57, no. 1
(July 2013): 33–39. https://doi.org/10.1111/lam.12082.
21 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
22 Rodriguez-Garcia, I., B. A. Silva-Espinoza, L. A. Ortega-Ramirez, J. M. Leyva, M. W.
Siddiqui, M. R. Cruz-Valenzuela, G. A. Gonzalez-Aguilar, and J. F. Ayala-Zavala.
“Oregano Essential Oil as an Antimicrobial and Antioxidant Additive in Food Products.”
Critical Reviews in Food Science and Nutrition 56, no. 10 (July 26, 2016): 1717–27.
https://doi.org/10.1080/10408398.2013.800832.
23 Lee, Jin-Hyung, Yong-Guy Kim, and Jintae Lee. “Carvacrol-Rich Oregano Oil and
Thymol-Rich Thyme Red Oil Inhibit Biofilm Formation and the Virulence of
Uropathogenic Escherichia Coli.” Journal of Applied Microbiology, October 5, 2017.
https://doi.org/10.1111/jam.13602.
24 Liu, Qing, Xiao Meng, Ya Li, Cai-Ning Zhao, Guo-Yi Tang, and Hua-Bin Li.
“Antibacterial and Antifungal Activities of Spices.” International Journal of Molecular
Sciences 18, no. 6 (June 16, 2017). https://doi.org/10.3390/ijms18061283.
25 Alvarez, Maria V., Luis A. Ortega-Ramirez, M. Melissa Gutierrez-Pacheco, A. Thalia
Bernal-Mercado, Isela Rodriguez-Garcia, Gustavo A. Gonzalez-Aguilar, Alejandra
Ponce, Maria Del R. Moreira, Sara I. Roura, and J. Fernando Ayala-Zavala. “Oregano
Essential Oil-Pectin Edible Films as Anti-Quorum Sensing and Food Antimicrobial
Agents.” Frontiers in Microbiology 5 (2014): 699.
https://doi.org/10.3389/fmicb.2014.00699.
26 Schillaci, Domenico, Edoardo Marco Napoli, Maria Grazia Cusimano, Maria Vitale,
and Andgiuseppe Ruberto. “Origanum Vulgare Subsp. Hirtum Essential Oil Prevented
Biofilm Formation and Showed Antibacterial Activity against Planktonic and Sessile
Bacterial Cells.” Journal of Food Protection 76, no. 10 (October 2013): 1747–52.
https://doi.org/10.4315/0362-028X.JFP-13-001.
27 Zou, Yi, Quanhang Xiang, Jun Wang, Jian Peng, and Hongkui Wei. “Oregano
Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins
Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig
Model.” BioMed Research International 2016 (2016): 5436738.
https://doi.org/10.1155/2016/5436738.
28 Bukovská, Alexandra, Stefan Cikos, Stefan Juhás, Gabriela Il’ková, Pavol Rehák,
and Juraj Koppel. “Effects of a Combination of Thyme and Oregano Essential Oils on
TNBS-Induced Colitis in Mice.” Mediators of Inflammation 2007 (2007): 23296.
https://doi.org/10.1155/2007/23296.
29 Tisserand, R. and Young. R. Essential Oil Safety: A Guide for Healthcare
Professionals. Second Ed. London, Churchill Livingstone, pp. 1290-1294.
30 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
31 Liu, Qing, Xiao Meng, Ya Li, Cai-Ning Zhao, Guo-Yi Tang, and Hua-Bin Li.
“Antibacterial and Antifungal Activities of Spices.” International Journal of Molecular
Sciences 18, no. 6 (June 16, 2017). https://doi.org/10.3390/ijms18061283.
32 Schmidt, Erich, Leopold Jirovetz, Katrin Wlcek, Gerhard Buchbauer, Velizar Gochev,
Tania Girova, Albena Stoyanova, and Margit Geissler. “Antifungal Activity of Eugenol
and Various Eugenol-Containing Essential Oils against 38 Clinical Isolates of Candida
Albicans.” Journal of Essential Oil Bearing Plants 10, no. 5 (January 1, 2007): 421–29.
https://doi.org/10.1080/0972060X.2007.10643575.
33 Srikaew, Benyapa, Narumol Matan, and Tanong Aewsiri. “Innovative Production of
Fungal Pulp from Trametes Versicolor and Its Application in a Fungal Paper Box
Containing Clove Oil.” Journal of Food Science and Technology 54, no. 10 (September
2017): 3058–64. https://doi.org/10.1007/s13197-017-2741-2.
34 Kim, Yong-Guy, Jin-Hyung Lee, Giyeon Gwon, Soon-Il Kim, Jae Gyu Park, and
Jintae Lee. “Essential Oils and Eugenols Inhibit Biofilm Formation and the Virulence of
Escherichia Coli O157:H7.” Scientific Reports 6 (November 3, 2016): 36377.
https://doi.org/10.1038/srep36377.
35 Rodrigues, T. G., A. Fernandes, J. P. B. Sousa, J. K. Bastos, and J. M. Sforcin. “In
Vitro and in Vivo Effects of Clove on pro-Inflammatory Cytokines Production by
Macrophages.” Natural Product Research 23, no. 4 (2009): 319–26.
https://doi.org/10.1080/14786410802242679.
36 Skogman, Barbro H., Sandra Hellberg, Christina Ekerfelt, Maria C. Jenmalm, Pia
Forsberg, Johnny Ludvigsson, Sven Bergström, and Jan Ernerudh. “Adaptive and Innate
Immune Responsiveness to Borrelia Burgdorferi Sensu Lato in Exposed Asymptomatic
Children and Children with Previous Clinical Lyme Borreliosis.” Clinical and
Developmental Immunology 2012 (2012). https://doi.org/10.1155/2012/294587.
37 Tisserand, R. and Young. R. Essential Oil Safety: A Guide for Healthcare
Professionals. Second Ed. London, Churchill Livingstone, pp. 909-913.
38 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
39 Utchariyakiat, Itsaraporn, Suvimol Surassmo, Montree Jaturanpinyo, Piyatip
Khuntayaporn, and Mullika Traidej Chomnawang. “Efficacy of Cinnamon Bark Oil and
Cinnamaldehyde on Anti-Multidrug Resistant Pseudomonas Aeruginosa and the
Synergistic Effects in Combination with Other Antimicrobial Agents.” BMC
Complementary and Alternative Medicine 16 (June 1, 2016): 158.
https://doi.org/10.1186/s12906-016-1134-9.
40 “Antibacterial and Antifungal Activities of Spices.” Accessed November 1, 2017.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486105/.
41 Al-Mariri, Ayman, George Saour, and Razan Hamou. “In Vitro Antibacterial Effects of
Five Volatile Oil Extracts against Intramacrophage Brucella Abortus 544.” Iranian Journal
of Medical Sciences 37, no. 2 (June 2012): 119–25.
42 Utchariyakiat, Itsaraporn, Suvimol Surassmo, Montree Jaturanpinyo, Piyatip
Khuntayaporn, and Mullika Traidej Chomnawang. “Efficacy of Cinnamon Bark Oil and
Cinnamaldehyde on Anti-Multidrug Resistant Pseudomonas Aeruginosa and the
Synergistic Effects in Combination with Other Antimicrobial Agents.” BMC
Complementary and Alternative Medicine 16 (June 1, 2016): 158.
https://doi.org/10.1186/s12906-016-1134-9.
43 Almeida, Leopoldina de Fátima Dantas de, Jacqueline Felipe de Paula, Rossana
Vanessa Dantas de Almeida, David Wynne Williams, Josimeri Hebling, and Yuri
Wanderley Cavalcanti. “Efficacy of Citronella and Cinnamon Essential Oils on Candida
Albicans Biofilms.” Acta Odontologica Scandinavica 74, no. 5 (July 2016): 393–98.
https://doi.org/10.3109/00016357.2016.1166261.
44 Han, Xuesheng, and Tory L. Parker. “Antiinflammatory Activity of Cinnamon
(Cinnamomum Zeylanicum) Bark Essential Oil in a Human Skin Disease Model.”
Phytotherapy Research: PTR 31, no. 7 (July 2017): 1034–38.
https://doi.org/10.1002/ptr.5822.
45 Kriz, R. Largo Bioscience Lyme-N Meeting. Herndon, VA. September 30, 2017
46 Cui, Haiying, Wei Li, Changzhu Li, Saritporn Vittayapadung, and Lin Lin. “Liposome
Containing Cinnamon Oil with Antibacterial Activity against Methicillin-Resistant
Staphylococcus Aureus Biofilm.” Biofouling 32, no. 2 (2016): 215–25.
https://doi.org/10.1080/08927014.2015.1134516.
47 Tisserand, R. and Young. R. Essential Oil Safety: A Guide for Healthcare
Professionals. Second Ed. London, Churchill Livingstone, pp. 889 – 893.
48 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
49 “Citronellal.” Wikipedia, November 25, 2016.
https://en.wikipedia.org/w/index.php?title=Citronellal&oldid=751381394.
50 Mahilrajan, Subajini, Jeyarani Nandakumar, Robika Kailayalingam, Nilushiny
Aloysius Manoharan, and SriThayalan SriVijeindran. “Screening the Antifungal Activity of
Essential Oils against Decay Fungi from Palmyrah Leaf Handicrafts.” Biological
Research 47 (August 15, 2014): 35. https://doi.org/10.1186/0717-6287-47-35.
51 “Efficacy of Citronella and Cinnamon Essential Oils on Candida Albicans Biofilms. –
PubMed – NCBI.” Accessed November 2, 2017.
https://www.ncbi.nlm.nih.gov/pubmed/27098375.
52 Kandimalla, Raghuram, Sanjeeb Kalita, Bhaswati Choudhury, Suvakanta Dash,
Kasturi Kalita, and Jibon Kotoky. “Chemical Composition and Anti-Candidiasis Mediated
Wound Healing Property of Cymbopogon Nardus Essential Oil on Chronic Diabetic
Wounds.” Frontiers in Pharmacology 7 (June 30, 2016).
https://doi.org/10.3389/fphar.2016.00198.
53 Tisserand, R. and Young. R. Essential Oil Safety: A Guide for Healthcare
Professionals. Second Ed. London, Churchill Livingstone, pp. 898 – 904.
54 Feng, Jie, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, and Ying
Zhang. “Selective Essential Oils from Spice or Culinary Herbs Have High Activity against
Stationary Phase and Biofilm Borrelia Burgdorferi.” Frontiers in Medicine 4 (2017).
https://doi.org/10.3389/fmed.2017.00169.
55 Giongo, Janice Luehring, Rodrigo de Almeida Vaucher, Michele Rorato Sagrillo,
Roberto Christ Vianna Santos, Marta M. M. F. Duarte, Vírginia Cielo Rech, Leonardo
Quintana Soares Lopes, et al. “Anti-Inflammatory Effect of Geranium Nanoemulsion
Macrophages Induced with Soluble Protein of Candida Albicans.” Microbial
Pathogenesis 110 (September 2017): 694–702.
https://doi.org/10.1016/j.micpath.2017.01.056.
56 Ouedrhiri, Wessal, Mounyr Balouiri, Samira Bouhdid, El Houssaine Harki, Sandrine
Moja, and Hassane Greche. “Antioxidant and Antibacterial Activities of Pelargonium
Asperum and Ormenis Mixta Essential Oils and Their Synergistic Antibacterial Effect.”
Environmental Science and Pollution Research International, July 22, 2017.
https://doi.org/10.1007/s11356-017-9739-1.
57 Bigos, Monika, Małgorzata Wasiela, Danuta Kalemba, and Monika Sienkiewicz.
“Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus
Aureus.” Molecules (Basel, Switzerland) 17, no. 9 (August 28, 2012): 10276–91.
https://doi.org/10.3390/molecules170910276.
58 Rosato, Antonio, Cesare Vitali, Nicolino De Laurentis, Domenico Armenise, and
Maria Antonietta Milillo. “Antibacterial Effect of Some Essential Oils Administered Alone
or in Combination with Norfloxacin.” Phytomedicine: International Journal of
Phytotherapy and Phytopharmacology 14, no. 11 (November 2007): 727–32.
https://doi.org/10.1016/j.phymed.2007.01.005.
59 Giongo, Janice Luehring, Rodrigo de Almeida Vaucher, Michele Rorato Sagrillo,
Roberto Christ Vianna Santos, Marta M. M. F. Duarte, Vírginia Cielo Rech, Leonardo
Quintana Soares Lopes, et al. “Anti-Inflammatory Effect of Geranium Nanoemulsion
Macrophages Induced with Soluble Protein of Candida Albicans.” Microbial
Pathogenesis 110 (September 2017): 694–702.
https://doi.org/10.1016/j.micpath.2017.01.056.
60 Tisserand, R. and Young. R. Essential Oil Safety: A Guide for Healthcare
Professionals. Second Ed. London, Churchill Livingstone, pp. 1029 – 1034.

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14 thoughts on “Five Essential Oils for Stopping Relapsing Symptoms Caused by Lyme Disease That Thrives Despite Multiple Antibiotics

    1. Greg Post author

      We individually test each patient for which oil works best for their condition. We then make our oils into a microparticle liposomes and have patients take it internally. Liposomes penetrate deeper into cells and through biofilms more effectively. Patients will start at a low dose and work their way up. They will lower their dose if they get a significant Herxheimer die off reaction.

      Reply
    1. Greg Post author

      We individually test each patient for which oil works best for their condition. We then make our oils into a microparticle liposomes and have patients take it internally. They will start at a low dose and work their way up. They will lower their dose if they get a significant Herxheimer die off reaction.

      Reply
  1. Jackie

    will this work if I mix it with coconut or olive oil as a carrier oil and massage it on my brother’s feet? He had Lyme and now has ALS, I’m not convinced the Lyme is eradicated.

    Reply
    1. Greg Post author

      The essential oils studies were in the lab. We make the essential oils into microparticles called liposomes so they can penetrate into cells and the brain. I don’t have any studies on these oils and ALS, so it’s impossible to estimate their ability to help your brother. You may want to consult with an essential oil therapist in your area for how to help your brother.

      Reply
    1. Greg Post author

      According to FDA Guidelines, I need to see patients in person before recommending dosing for essential oils. Every patient has a different sensitivity to the oils so dosing can vary.

      Reply
  2. Martini

    There is an error in this text ( part: Anti-Lyme Persister Essential Oil #5: Geranium Bourbon) Interleukin-10 in anti-inflammatory not inflammatory. IL-10 induces all anti-inflammatory cascade. Interleukin which is inflammatory is IL-1 not 10.

    Reply

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